Sakac V, Vodopivec S, Mitić I, Ićurup Z, Felle D
Klinika za nefrologiju i klinicku imunologiju, Institut za interne bolesti, Medicinski fakultet, Novi Sad.
Med Pregl. 1996;49(5-6):229-32.
Systemic vasculitis presents a group of clinically pathologic syndromes with acute inflammatory process in its basis which commonly occurs on small blood vessels destroying their walls with fibrinoid necrosis. It often occurs on several organs and systems depending on the form, size and number of the diseased blood vessels. This paper is a case report on a female patient suffering from a serious systemic necrotizing vasculitis with clinically demonstrated ulceronecrotizing skin changes and purpura together with appearance of coronary ischemia; rhythmic disorders of heart rate and gastrointestinal bleeding and cardiac arrest in one moment. It contains a description of the course of the disease and a good result after application of immunosuppressive therapy with high doses of corticosteroids, cyclosporin A and plasmaphereses.
系统性血管炎是一组以急性炎症过程为基础的临床病理综合征，通常发生于小血管，导致血管壁破坏并伴有纤维素样坏死。根据病变血管的形式、大小和数量，它常累及多个器官和系统。本文是一例女性患者的病例报告，该患者患有严重的系统性坏死性血管炎，临床上表现为溃疡性坏死性皮肤改变、紫癜以及冠状动脉缺血；同时出现心率节律紊乱、胃肠道出血，并有一次心脏骤停。文中描述了疾病的病程以及在应用大剂量皮质类固醇、环孢素A免疫抑制治疗和血浆置换后的良好效果。
