de Gregorio Miguel Angel, Laborda Alicia, Higuera María Teresa, Lostale Fernando, Gómez-Arrue Javier, Serrano Carolina, Martínez Miguel Angel, Viloria Américo
Unidad de Cirugía Mínimamente Invasiva Guiada por Imagen, Facultad de Veterinaria, Universidad de Zaragoza, España.
Arch Bronconeumol. 2008 Nov;44(11):591-6. doi: 10.1016/s1579-2129(08)60112-3.
To study the feasibility and safety of removing retrievable Günther-Tulip vena cava filters (GTFs) 90 days after their implantation in an ovine model.
Thirty GTFs were implanted in 30 ewes and retrieval was attempted at 90 days. Conventional cavography was performed in all cases before and after retrieval in order to evaluate inferior vena cava patency and record dimensions. The presence of complications related to placement and retrieval of the filter from the inferior vena cava was also recorded. The force required to remove the filters was measured using a modified commercial dynamometer adapted to the GTF retrieval set. Histologic study focused on the inferior vena cava wall.
Implantation was performed successfully in all cases (100%). One ewe developed a small focus of thrombosis around 1 of the legs of the filter and another presented a small thrombus within the filter. Retrieval of the filter was attempted in all 30 sheep at 90 days and the result was satisfactory in all but 1 case (96.6%). None of the GTFs required a force greater than 12 N to disengage the hooks of the filter from the wall. No complications were detected on venacavography or at autopsy. Variable degrees of fibrosis were observed in the histologic study.
Retrieval of GTFs 90 days after implantation in an ovine model was feasible, safe, and easy, and required little force (median, 4.2 N).
研究在绵羊模型中植入可回收的 Günther-Tulip 下腔静脉滤器（GTF）90 天后取出的可行性和安全性。
将 30 个 GTF 植入 30 只母羊体内，并在 90 天时尝试取出。在取出前后对所有病例进行常规腔静脉造影，以评估下腔静脉通畅情况并记录尺寸。还记录了与滤器在下腔静脉中的放置和取出相关的并发症。使用适配于 GTF 取出装置的改良商用测力计测量取出滤器所需的力。组织学研究聚焦于下腔静脉壁。
所有病例（100%）均成功植入。一只母羊在滤器的一条腿周围形成了一个小血栓灶，另一只母羊在滤器内出现了一个小血栓。在 90 天时对所有 30 只绵羊尝试取出滤器，除 1 例（96.6%）外，其余结果均令人满意。没有一个 GTF 需要大于 12 N 的力来使滤器的钩子与血管壁分离。在腔静脉造影或尸检中未检测到并发症。在组织学研究中观察到不同程度的纤维化。
在绵羊模型中植入 GTF 90 天后取出是可行、安全且容易的，并且所需力量很小（中位数为 4.2 N）。
