第11章。骨髓来源细胞在肿瘤血管生成和转移进展中的作用。
Chapter 11. The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression.
作者信息
Papaspyridonos Marianna, Lyden David
机构信息
Department of Pediatrics and Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, USA.
出版信息
Methods Enzymol. 2008;444:255-69. doi: 10.1016/S0076-6879(08)02811-5.
Abstract
Tumor angiogenesis is orchestrated by a complex set of secreted factors and collaboration between many different cell types. This chapter discusses the role of tumor-secreted angiogenic factors that are responsible for the recruitment of bone marrow-derived cells (BMDCs) at tumor sites and their role in tumor angiogenesis and progression.
摘要
肿瘤血管生成是由一系列复杂的分泌因子以及多种不同细胞类型之间的协同作用所精心调控的。本章将讨论肿瘤分泌的血管生成因子在肿瘤部位募集骨髓来源细胞（BMDCs）中的作用，以及它们在肿瘤血管生成和进展中的作用。
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