Peltzer Karl, Mosala Thabang, Dana Pelisa, Fomundam Henry
Health Systems Research Unit, Social Aspect of HIV/AIDS and Health, Human Sciences Research Council, Pretoria, South Africa.
J Assoc Nurses AIDS Care. 2008 Nov-Dec;19(6):450-60. doi: 10.1016/j.jana.2008.05.006.
The aim of this study was to investigate the implementation of a prevention of mother-to-child transmission (PMTCT) program and to evaluate the uptake and adherence to single-dose nevirapine in a cohort sample that had undergone PMTCT in five public clinics in a resource-poor setting, Quakeni Local Service Area, O.R. Tambo District in the Eastern Cape, South Africa. Results indicated that 116 women (15.3% of the sample) were infected with HIV, 642 (84.7%) were uninfected, and 552 (42.1%) had an unknown HIV status. Almost all of the women had received information about HIV and HIV testing prenatally, but 552 (42%) had not been tested for HIV, and their HIV status was unknown. Only 66 (57%) of the HIV-infected pregnant women had been provided with nevirapine. It is recommended that the quality of HIV counseling be improved and the program of maternal self-medication with nevirapine tablets at onset of labor and maternal provision of nevirapine syrup to newborns be encouraged.
本研究的目的是调查预防母婴传播（PMTCT）项目的实施情况，并评估在南非东开普省奥.R.坦博区夸凯尼当地服务区资源匮乏环境下的五家公共诊所中接受过PMTCT的队列样本中对单剂量奈韦拉平的接受程度和依从性。结果表明，116名女性（占样本的15.3%）感染了艾滋病毒，642名（84.7%）未感染，552名（42.1%）艾滋病毒感染状况未知。几乎所有女性在产前都收到了有关艾滋病毒和艾滋病毒检测的信息，但552名（42%）未接受艾滋病毒检测，其艾滋病毒感染状况未知。只有66名（57%）感染艾滋病毒的孕妇获得了奈韦拉平。建议提高艾滋病毒咨询质量，并鼓励实施产妇在临产前自行服用奈韦拉平片剂以及产妇向新生儿提供奈韦拉平糖浆的项目。
