Groll Andreas H, McNeil Grist Liz
Infectious Disease Research Program, Centre for Bone Marrow Transplantation and Department of Paediatric Haematology/Oncology, University Children's Hospital, Münster, Germany.
Int J Antimicrob Agents. 2009 Feb;33(2):101-4. doi: 10.1016/j.ijantimicag.2008.08.014. Epub 2008 Nov 12.
New, aggressive forms of immunosuppression and an increasing population of patients at risk provide fertile ground for opportunistic invasive fungal infections (IFIs). Particularly challenging is the changing epidemiology of IFIs: rare pathogens are now more common and resistant strains are emerging among species that are generally considered to be sensitive. Staying one step ahead of this evolving epidemiology is a major task and some 400 delegates, from 44 countries, learned that although there has been considerable progress, more is needed.
新型、强效免疫抑制形式以及风险患者群体的不断增加,为机会性侵袭性真菌感染(IFI)提供了滋生土壤。IFI不断变化的流行病学情况尤其具有挑战性:罕见病原体如今更为常见,而且在通常被认为敏感的菌种中也出现了耐药菌株。在这种不断演变的流行病学情况中保持领先是一项重大任务,来自44个国家的约400名代表了解到,尽管已经取得了相当大的进展,但仍有更多工作需要开展。