Jang Yoon Seok, Kang Myung-Koo
Department of Otorhinolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
Otol Neurotol. 2009 Jan;30(1):95-100. doi: 10.1097/MAO.0b013e31818f5777.
To evaluate the relationship between bone mineral density (BMD) and clinical features in women with idiopathic benign paroxysmal positional vertigo (IBPPV).
Prospective study.
Tertiary referral center.
Patients with BMD measurements made after a diagnosis of IBPPV were included. The IBPPV (n = 78) and control groups (n = 177) were divided into ordinal age categories of similar size. Group A (n = 20) patients were aged 20 to 39 years, Group B (n = 21) patients were aged 40 to 49 years, Group C (n = 18) patients were aged 50 to 59 years, and Group D (n = 19) patients were aged 60 to 69 years.
In each age range, the BMD values were compared according to the number of canalith repositioning maneuvers (CRMs) or the presence of recurrence. We divided all patients into 2 groups with the normal and abnormal BMD values and compared both groups based on the number of CRMs or the frequency of recurrence.
The BMD value, the number of CRMs, and the presence of recurrence.
In Groups A, B, and C, there was a significant difference in the BMD values between the control, 1-visit, and 2-or-more-visits subgroups. In Group D, the 2-or-more-visits subgroup had a lower BMD value than other subgroups. The difference in the number of CRMs between the normal and abnormal BMD groups was significant. In Groups A and B, there was a significant difference in the BMD values between the control, first-attack, and recurrent-attacks subgroups. In Groups C and D, the recurrent-attacks subgroup had lower BMD values than other subgroups. The difference in the frequency of recurrence between the normal and abnormal BMD groups was significant.
Patients with IBPPV had lower BMD values compared with control subjects, and patients with low BMD values showed a significant increase in the number of CRMs required and the recurrence rate.
评估特发性良性阵发性位置性眩晕（IBPPV）女性患者的骨密度（BMD）与临床特征之间的关系。
前瞻性研究。
三级转诊中心。
纳入确诊为IBPPV后进行骨密度测量的患者。将IBPPV组（n = 78）和对照组（n = 177）分为年龄相近的有序类别。A组（n = 20）患者年龄为20至39岁，B组（n = 21）患者年龄为40至49岁，C组（n = 18）患者年龄为50至59岁，D组（n = 19）患者年龄为60至69岁。
在每个年龄范围内，根据半规管耳石复位手法（CRMs）的次数或复发情况比较骨密度值。我们将所有患者分为骨密度值正常和异常两组，并根据CRMs次数或复发频率对两组进行比较。
骨密度值、CRMs次数和复发情况。
在A、B和C组中，对照组、就诊1次组和就诊2次或更多次组之间的骨密度值存在显著差异。在D组中，就诊2次或更多次组的骨密度值低于其他亚组。骨密度正常组和异常组之间的CRMs次数差异显著。在A和B组中，对照组、首次发作组和复发组之间的骨密度值存在显著差异。在C和D组中，复发组的骨密度值低于其他亚组。骨密度正常组和异常组之间的复发频率差异显著。
与对照组相比，IBPPV患者的骨密度值较低，骨密度值低的患者所需的CRMs次数和复发率显著增加。
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