Suppr超能文献

高血压及相关危险因素对良性阵发性位置性眩晕复发的发病及缓解率的影响:一项6年回顾性研究

The Impact of Hypertension and Related Risk Factors on the Onset and Resolution Rates of Benign Paroxysmal Positional Vertigo Recurrence: A 6-Year Retrospective Study.

作者信息

Micarelli Alessandro, Granito Ivan, Micarelli Riccardo Xavier, Alessandrini Marco

机构信息

Unit of Neuroscience, Rehabilitation and Sensory Organs, UNITER ONLUS, 00153 Rome, Italy.

Department of Clinical Sciences and Translational Medicine, ENT Unit, University of Rome Tor Vergata, 00133 Rome, Italy.

出版信息

Neurol Int. 2025 May 25;17(6):82. doi: 10.3390/neurolint17060082.

Abstract

Due to conflicting results about hypertension and the involvement of associated risk factors in the presentation of idiopathic benign paroxysmal positional vertigo recurrence (R-BPPV), this study aimed to explore possible associations between the resolution rate (RR) and recurrence onset (RO) of R-BPPV, as well as hypertension classification and stages and demographic characteristics. A total of 1201 medical records from patients collected over a 6-year span who first presented with R-BPPV were retrospectively evaluated regarding blood pressure (BP) presentation and associated risk factors. R-BPPV included patients treated with necessary canalith repositioning procedures (CRPs) and followed up with for 12 months. The RO and RR were evaluated when comparing patients sub-grouped by current classification and staging. The association between the RO and RR and many prognostic factors, including the presence of cardio- and neuro-vascular risks, was examined via multiple regression analysis. Among the 857 included patients with R-BPPV, 211 presented with an optimal/normal BP, 210 were found to have a high-normal BP, 222 were classified with Grade 1 hypertension, and 214 were found to have Grade 2 hypertension. Significant ( < 0.05) progressive earlier presentations and increases in needed CRPs were found with the respective increase in BP subgroups. For the RO, the correlation was statistically significant for age and gender, while for the RR, the correlation was statistically significant for age and hypertension stage. This study demonstrates for the first time that clinical consequences of R-BPPV are strongly associated with cardio-, neuro-vascular, and socio-demographic risk factors, which are commonly involved in R-BPPV occurrence.

摘要

由于关于高血压以及相关危险因素在特发性良性阵发性位置性眩晕复发(R - BPPV)中的作用存在相互矛盾的结果,本研究旨在探讨R - BPPV的缓解率(RR)和复发起始(RO)之间可能存在的关联,以及高血压的分类、分期和人口统计学特征。回顾性评估了在6年期间收集的1201例首次出现R - BPPV患者的病历,以了解血压(BP)表现和相关危险因素。R - BPPV包括接受必要的耳石复位程序(CRP)治疗并随访12个月的患者。在比较按当前分类和分期分组的患者时评估RO和RR。通过多元回归分析检查RO和RR与许多预后因素之间的关联,包括心血管和神经血管风险的存在情况。在纳入的857例R - BPPV患者中,211例血压最佳/正常,210例血压处于高正常范围,222例被分类为1级高血压,214例被发现患有2级高血压。随着血压亚组的相应增加,发现显著(<0.05)的进展性早期表现和所需CRP的增加。对于RO,年龄和性别之间的相关性具有统计学意义,而对于RR,年龄和高血压分期之间的相关性具有统计学意义。本研究首次表明,R - BPPV的临床后果与心血管、神经血管和社会人口统计学危险因素密切相关,这些因素通常与R - BPPV的发生有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cba/12196472/8775c7165652/neurolint-17-00082-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验