Kaleda V G, Lebedeva I S, Barkhatova A N, Omel'chenko M A, Golubev S A, Sidorova M A
Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(11):21-7.
The dynamics of neuropsychological and neurophysiological markers of cognitive functions was analyzed in the groups of the first-episode young male patients. Totally 90 patients have been studied. At the early stage of remission, the improvement of the processes associated with voluntary regulation of cognition caused by the activity of the wide circuit of cortical and subcortical structures was found. At the same time, the more automated processes related mostly with the temporal brain areas remained abnormal. The peculiarities of neurocognitive dynamics during the development of the remission were revealed in the groups of patients with different syndrome structure of the first episode (catatonic, delusion/hallucination, affective-delusion).
对首发年轻男性患者组的认知功能神经心理学和神经生理学标志物的动态变化进行了分析。共研究了90例患者。在缓解早期，发现由皮质和皮质下结构的广泛回路活动引起的与认知的自主调节相关的过程有所改善。与此同时，主要与颞叶脑区相关的自动化程度更高的过程仍存在异常。在首发具有不同综合征结构（紧张症、妄想/幻觉、情感妄想）的患者组中，揭示了缓解期发展过程中神经认知动态变化的特点。
