• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阴茎癌的保器官手术

Organ-preserving surgery for penile carcinoma.

作者信息

Martins Francisco E, Rodrigues Raul N, Lopes Tomé M

机构信息

Departamento de Urologia, Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Universidade de Lisboa, Avenida Professor Egas Moniz, 1649-035 Lisboa, Portugal.

出版信息

Adv Urol. 2008;2008:634216. doi: 10.1155/2008/634216. Epub 2008 Nov 4.

DOI:10.1155/2008/634216
PMID:19009032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2581733/
Abstract

Introduction. Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. Innovative surgical techniques have focused on penile preservation in well-selected patients to minimize physical disfigurement and consequently maximize quality of life. The objective of this article is to define the current status of these organ-preserving surgical options for penile carcinoma. Materials and Methods. An extensive review of the Pubmed literature was performed to find articles discussing only reconstructive surgery which have contributed significantly to change traditional, frequently mutilating treatments, to develop less disfiguring surgery, and to improve patients' quality of life over the last two decades. Results. Several articles were included in this analysis in which a major contribution to the change in therapy was thought to have occurred and was documented as beneficial. Some articles reported novel techniques of less-mutilating surgery involving different forms of glans reconstruction with the use of flaps or grafts. The issue of safe surgical margins was also addressed. Conclusion. The development of less-disfiguring techniques allowing phallus preservation has reduced the negative impact on functional and cosmetic outcomes of amputation without sacrificing oncological objectives in appropriately selected patients based on stage, grade, and location of the tumour. Until more prospective studies are available and solid evidence is documented, organ preservation should be offered with caution.

摘要

引言。阴茎癌传统上通过手术切除或根治性放疗进行治疗,这两种方法都会对患者的生活造成毁灭性的解剖学、功能和心理影响。创新的手术技术致力于在精心挑选的患者中保留阴茎,以尽量减少身体畸形,从而最大限度地提高生活质量。本文的目的是明确这些阴茎癌保留器官手术方案的现状。材料与方法。对PubMed文献进行了广泛回顾,以查找仅讨论重建手术的文章,这些文章在过去二十年中对改变传统的、常常造成毁容的治疗方法、发展创伤较小的手术以及改善患者生活质量做出了重大贡献。结果。本分析纳入了几篇文章,其中认为对治疗方法的改变有重大贡献且记录为有益。一些文章报道了创伤较小的手术新技术,包括使用皮瓣或移植物进行不同形式的龟头重建。还讨论了安全手术切缘的问题。结论。在基于肿瘤分期、分级和位置进行适当选择的患者中,创伤较小的保留阴茎技术的发展减少了截肢对功能和美容效果的负面影响,同时不牺牲肿瘤学目标。在有更多前瞻性研究且有确凿证据记录之前,应谨慎提供器官保留治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1b/2581733/96dc1b86ca71/AU2008-634216.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1b/2581733/e80137d58384/AU2008-634216.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1b/2581733/96dc1b86ca71/AU2008-634216.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1b/2581733/e80137d58384/AU2008-634216.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1b/2581733/96dc1b86ca71/AU2008-634216.002.jpg

相似文献

1
Organ-preserving surgery for penile carcinoma.阴茎癌的保器官手术
Adv Urol. 2008;2008:634216. doi: 10.1155/2008/634216. Epub 2008 Nov 4.
2
[Reconstructive surgery in penile cancer].[阴茎癌的重建手术]
Urologe A. 2018 Apr;57(4):428-434. doi: 10.1007/s00120-018-0610-x.
3
Penile cancer: organ-sparing techniques.阴茎癌:保器官技术。
BJU Int. 2014 Dec;114(6):799-805. doi: 10.1111/bju.12338. Epub 2014 Oct 16.
4
Penile preserving surgery and surgical strategies to maximize penile form and function in penile cancer: recommendations from the United Kingdom experience.
World J Urol. 2009 Apr;27(2):179-87. doi: 10.1007/s00345-008-0312-x. Epub 2008 Jul 18.
5
What surgical resection margins are required to achieve oncological control in men with primary penile cancer?在原发性阴茎癌男性患者中,为实现肿瘤学控制需要何种手术切缘?
BJU Int. 2005 Nov;96(7):1040-3. doi: 10.1111/j.1464-410X.2005.05769.x.
6
Penile cancer and phallus preservation strategies: a review of current literature.阴茎癌与阴茎保全策略:文献复习
BJU Int. 2013 Nov;112 Suppl 2:21-6. doi: 10.1111/bju.12205.
7
Primary penile cancer organ sparing treatment.原发性阴茎癌的保留器官治疗。
Cent European J Urol. 2016;69(4):377-383. doi: 10.5173/ceju.2016.890. Epub 2016 Oct 17.
8
Organ-sparing surgery for invasive penile cancer: early follow-up data.浸润性阴茎癌的保留器官手术:早期随访数据。
BJU Int. 2004 Dec;94(9):1253-7. doi: 10.1111/j.1464-410X.2004.05153.x.
9
Organ-preserving surgery for penile cancer: description of techniques and surgical outcomes.阴茎癌保器官手术:技术描述及手术结果。
BJU Int. 2012 Dec;110(11):1792-5. doi: 10.1111/j.1464-410X.2012.11084.x. Epub 2012 May 2.
10
Psychosocial impact of penile carcinoma.阴茎癌的社会心理影响。
Transl Androl Urol. 2017 Oct;6(5):874-878. doi: 10.21037/tau.2017.07.24.

引用本文的文献

1
Hyperbaric Oxygen Therapy for Reconstructive Urology Wounds: A Case Series.高压氧疗法用于重建泌尿外科伤口:病例系列
Res Rep Urol. 2021 Dec 20;13:841-852. doi: 10.2147/RRU.S331161. eCollection 2021.
2
Radical penectomy, a compromise for life: results from the PECAD study.根治性阴茎切除术:对生命的一种妥协——PECAD研究结果
Transl Androl Urol. 2020 Jun;9(3):1306-1313. doi: 10.21037/tau.2020.04.04.
3
Clinical outcomes of glansectomy with split-thickness skin graft reconstruction for localized penile cancer.局部阴茎癌行阴茎头切除术加中厚皮片移植重建术的临床疗效

本文引用的文献

1
Distal urethral reconstruction of the glans for penile carcinoma: results of a novel technique at 1-year of followup.阴茎癌龟头远端尿道重建:一项新技术1年随访结果
J Urol. 2007 Sep;178(3 Pt 1):941-4. doi: 10.1016/j.juro.2007.05.059. Epub 2007 Jul 16.
2
Sexual function after partial penectomy for penile cancer.阴茎癌部分阴茎切除术后的性功能
Urology. 2005 Dec;66(6):1292-5. doi: 10.1016/j.urology.2005.06.081.
3
What surgical resection margins are required to achieve oncological control in men with primary penile cancer?
Can Urol Assoc J. 2020 Oct;14(10):E482-E486. doi: 10.5489/cuaj.6277.
4
Prognostic Factors for Penile Cancer and Survival in Response to Multimodality Therapy.阴茎癌的预后因素及多模式治疗后的生存情况
Res Rep Urol. 2020 Feb 12;12:29-34. doi: 10.2147/RRU.S238147. eCollection 2020.
5
Primary penile cancer organ sparing treatment.原发性阴茎癌的保留器官治疗。
Cent European J Urol. 2016;69(4):377-383. doi: 10.5173/ceju.2016.890. Epub 2016 Oct 17.
6
Organ Preservation Surgery for Carcinoma Penis.阴茎癌的器官保留手术
Indian J Surg Oncol. 2017 Mar;8(1):59-63. doi: 10.1007/s13193-016-0573-6. Epub 2016 Dec 20.
7
A case of synchronous double primary cancer of the penis and urinary bladder.一例阴茎和膀胱同步双原发癌。
Cancer Res Treat. 2010 Mar;42(1):53-6. doi: 10.4143/crt.2010.42.1.53. Epub 2010 Mar 31.
在原发性阴茎癌男性患者中,为实现肿瘤学控制需要何种手术切缘?
BJU Int. 2005 Nov;96(7):1040-3. doi: 10.1111/j.1464-410X.2005.05769.x.
4
Conservative surgery for penile cancer: subtotal glans excision without grafting.阴茎癌的保守手术:不进行移植的龟头部分切除术。
BJU Int. 2005 Oct;96(6):911-2. doi: 10.1111/j.1464-410X.2005.05751.x.
5
Organ-sparing surgery for invasive penile cancer: early follow-up data.浸润性阴茎癌的保留器官手术:早期随访数据。
BJU Int. 2004 Dec;94(9):1253-7. doi: 10.1111/j.1464-410X.2004.05153.x.
6
EAU Guidelines on Penile Cancer.欧洲泌尿外科学会阴茎癌指南。
Eur Urol. 2004 Jul;46(1):1-8. doi: 10.1016/j.eururo.2004.03.007.
7
Multi-institutional long-term experience with conservative surgery for invasive penile carcinoma.多机构关于浸润性阴茎癌保守手术的长期经验。
J Urol. 2003 Feb;169(2):500-2. doi: 10.1097/01.ju.0000043808.58188.52.
8
Penile carcinoma. Is Nd:YAG laser therapy radical enough?阴茎癌。钕钇铝石榴石激光疗法足够根治吗?
J Urol. 2002 Dec;168(6):2418-21; discussion 2421. doi: 10.1016/S0022-5347(05)64158-4.
9
Laser therapy for carcinoma in situ of the penis.阴茎原位癌的激光治疗
J Urol. 2001 Nov;166(5):1670-1. doi: 10.1097/00005392-200111000-00013.
10
Glanuloplasty with scrotal flap for partial penectomy.阴囊皮瓣阴茎成形术治疗部分阴茎切除术
J Urol. 2001 Sep;166(3):887-9.