用于构建环状类肽微阵列的编码组合文库。
Encoded combinatorial libraries for the construction of cyclic peptoid microarrays.
作者信息
Kwon Yong-Uk, Kodadek Thomas
机构信息
Division of Translational Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9185, USA.
出版信息
Chem Commun (Camb). 2008 Nov 30(44):5704-6. doi: 10.1039/b812735b. Epub 2008 Oct 16.
Abstract
A "one bead two compound" approach to the synthesis of encoded cyclic peptoid libraries is reported.
摘要
报道了一种用于合成编码环肽库的“一珠双化合物”方法。
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2
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Biopolymers. 2008 Aug;89(8):653-67. doi: 10.1002/bip.20983.
3
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4
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