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[副球孢子菌病肺部表现的临床-放射学分离现象]

[Clinical-radiological dissociation in lung manifestations of paracoccidioidomycosis].

作者信息

Gomes Elenice, Wingeter Márcia Arias, Svidzinski Terezinha Inez Estivalet

机构信息

Clínica de Fisioterapia, Centro Universitário de Maringá, Maringá, PR.

出版信息

Rev Soc Bras Med Trop. 2008 Sep-Oct;41(5):454-8. doi: 10.1590/s0037-86822008000500004.

DOI:10.1590/s0037-86822008000500004
PMID:19009185
Abstract

Lungs are among the main sites affected by paracoccidioidomycosis. However, the alterations are not always easy to differentiate from other respiratory disorders. The objectives of the present study were to investigate the frequency of lung impairment in paracoccidioidomycosis cases and to investigate whether any clinical-radiological association exists. A retrospective study was carried out from March 1996 to November 2006, among patients with paracoccidioidomycosis at the Regional University Hospital of Maringá, Paraná, Brazil. Over this period, 45 cases were confirmed, of which 79.5% presented radiological abnormalities on chest X-rays, and four of them also presented pulmonary tuberculosis. Out of the total of 40 patients with paracoccidioidomycosis alone, 57.5% presented respiratory clinical manifestations, whereas 77.5% presented radiological abnormalities, thus demonstrating clinical-radiological dissociation. On the other hand, 80.6% of the patients who presented radiological abnormalities said that they smoked. We concluded that although morphological abnormalities in the lungs are frequent, they do not always correspond to respiratory signs and symptoms and cannot easily be attributed exclusively to paracoccidioidomycosis.

摘要

肺部是受副球孢子菌病影响的主要部位之一。然而,这些病变并不总是容易与其他呼吸系统疾病相区分。本研究的目的是调查副球孢子菌病病例中肺部损伤的发生率,并调查是否存在任何临床 - 放射学关联。对1996年3月至2006年11月期间巴西巴拉那州马林加地区大学医院的副球孢子菌病患者进行了一项回顾性研究。在此期间,确诊了45例病例,其中79.5%的患者胸部X线检查有放射学异常,其中4例还患有肺结核。在仅患有副球孢子菌病的40名患者中,57.5%有呼吸系统临床表现,而77.5%有放射学异常,从而显示出临床 - 放射学分离。另一方面,出现放射学异常的患者中有80.6%表示他们吸烟。我们得出的结论是,虽然肺部形态学异常很常见,但它们并不总是与呼吸体征和症状相符,也不能轻易地完全归因于副球孢子菌病。

相似文献

1
[Clinical-radiological dissociation in lung manifestations of paracoccidioidomycosis].[副球孢子菌病肺部表现的临床-放射学分离现象]
Rev Soc Bras Med Trop. 2008 Sep-Oct;41(5):454-8. doi: 10.1590/s0037-86822008000500004.
2
The gamut of progressive pulmonary paracoccidioidomycosis.进行性肺副球孢子菌病的全貌。
Mycopathologia. 1981 Aug 7;75(2):65-74. doi: 10.1007/BF00505780.
3
Pulmonary paracoccidioidomycosis: radiology and clinical-epidemiological evaluation.肺副球孢子菌病:放射学和临床流行病学评估。
Rev Soc Bras Med Trop. 2010 Nov-Dec;43(6):651-6. doi: 10.1590/s0037-86822010000600010.
4
Chronic pulmonary paracoccidioidomycosis in the state of Rio Grande do Sul, Brazil.巴西南里奥格兰德州的慢性肺副球孢子菌病。
Mycopathologia. 1999;145(2):63-7. doi: 10.1023/a:1007075524924.
5
Progressive pulmonary paracoccidioidomycosis a study of 34 cases observed in Rio Grande do Sul (Brazil).进行性肺副球孢子菌病:对巴西南里奥格兰德州观察到的34例病例的研究
Mycopathologia. 1978 Apr 14;63(1):53-6. doi: 10.1007/BF00473160.
6
Fine needle aspiration in the diagnosis of pulmonary paracoccidioidomycosis.细针穿刺抽吸术在肺副球孢子菌病诊断中的应用
Mycopathologia. 1998;143(2):65-9. doi: 10.1023/a:1006973309834.
7
[Thoracic radiologic aspects in paracoccidioidomycosis].
Rev Inst Med Trop Sao Paulo. 1992 Mar-Apr;34(2):107-15.
8
[A case of chronic pulmonary paracoccidioidomycosis].[一例慢性肺副球孢子菌病]
Nihon Kokyuki Gakkai Zasshi. 2004 Jul;42(7):629-33.
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Lung cysts in chronic paracoccidioidomycosis.慢性球孢子菌病中的肺囊肿。
J Bras Pneumol. 2013 May-Jun;39(3):368-72. doi: 10.1590/S1806-37132013000300015.
10
[Paracoccidioidomycosis: radiologic and pulmonary study in 58 cases].[副球孢子菌病:58例的放射学与肺部研究]
Rev Inst Med Trop Sao Paulo. 1991 Jul-Aug;33(4):267-76.

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Disseminated paracoccidioidomycosis diagnosis based on oral lesions.基于口腔病变的播散性副球孢子菌病诊断
Contemp Clin Dent. 2014 Apr;5(2):213-6. doi: 10.4103/0976-237X.132340.
2
Western blotting is an efficient tool for differential diagnosis of paracoccidioidomycosis and pulmonary tuberculosis.蛋白质印迹法是用于副球孢子菌病和肺结核鉴别诊断的有效工具。
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