Noguchi Thyroid Clinic & Hospital Foundation, 6-33 Noguchi-Nakamachi, Beppu, Oita 874-0932, Japan.
World J Surg. 2009 Mar;33(3):394-6. doi: 10.1007/s00268-008-9813-4.
For papillary thyroid cancer, lymph node excision may be less important for smaller tumors and rather limited node excision might be sufficient to prevent recurrence.
We compared patients who had undergone modified radical neck dissection with patients who had undergone limited node basin excision. Between 1967 and 1996, 4966 patients at our institution had resection of pure papillary carcinoma tumors larger than 11 mm.
In patients whose tumors were larger than 25 mm without local adhesion, modified radical neck dissection had a significantly better prognosis compared to that of more limited node excision. For patients with a primary tumor larger than 11 mm, modified radical had a better prognosis than partial node excision only if there was adhesion or invasion to the recurrent nerve, jugular vein, common carotid artery, vagus nerve, or trachea.
The size of papillary cancer of the thyroid directly affects prognosis and the role of nodal dissection.
对于甲状腺乳头状癌,淋巴结切除对于较小的肿瘤可能不太重要,而有限的淋巴结切除可能足以预防复发。
我们比较了接受改良根治性颈清扫术的患者和接受有限淋巴结盆地切除术的患者。在 1967 年至 1996 年间,我们机构的 4966 例患者切除了直径大于 11 毫米的纯乳头状癌肿瘤。
在无局部粘连的肿瘤大于 25 毫米的患者中,与更有限的淋巴结切除相比,改良根治性颈清扫术的预后明显更好。对于原发肿瘤大于 11 毫米的患者,如果有粘连或侵犯喉返神经、颈内静脉、颈总动脉、迷走神经或气管,改良根治术的预后优于部分淋巴结切除术。
甲状腺乳头状癌的大小直接影响预后和淋巴结清扫的作用。