Suppr超能文献

[原发性切除术后复发性甲状腺癌的外科治疗]

[Surgical treatment of recurrent thyroid carcinoma after primary resection].

作者信息

Kohara N, Furui J, Tomioka T, Motojima K, Tsunoda T, Kanematsu T

机构信息

Second Department of Surgery, Nagasaki University School of Medicine, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1993 Aug;94(8):847-52.

PMID:8377761
Abstract

Twenty-six patients who underwent the second operation for recurrent thyroid carcinoma were reviewed. 1) Three surgical interventions; dissection of local lymph nodes, modified neck dissection and extended neck dissection, for the patients with recurrent thyroid carcinoma were performed. Among these patients, recurrence of thyroid carcinoma occurred again in 14 (74%) of 19 patients with dissection of local lymph nodes, 15 (63%) of 24 with modified neck dissection, 2 (22%) of 9 with extended neck dissection. Patients with extended neck dissection had significantly less local recurrence than those with other procedures (p < 0.05). 2) Lymph node recurrence on the resected area occurred in 11 (73%) of 14 patients with dissection of local lymph nodes. Ten (67%) of 15 patients with modified neck dissection had recurrence beyond the dissected area. 3) In well differentiated carcinoma, there was recurrence in 5 (62%) of 8 patients with dissection of local lymph nodes, and in 4 (31%) of 13 with modified neck dissection. In contrast, in poorly differentiated carcinoma, we found recurrence in 8 (89%) of 9, and 10 (100%) of 10, respectively. However, in only one (20%) patient with extended neck dissection, recurrence occurred. We conclude that extended neck dissection should be the procedure of choice in patients with recurrent thyroid cancer whenever feasible.

摘要

回顾了26例接受复发性甲状腺癌二次手术的患者。1)对复发性甲状腺癌患者进行了三种手术干预:局部淋巴结清扫、改良颈部清扫和扩大颈部清扫。在这些患者中,19例行局部淋巴结清扫的患者中有14例(74%)甲状腺癌再次复发,24例行改良颈部清扫的患者中有15例(63%)复发,9例行扩大颈部清扫的患者中有2例(22%)复发。行扩大颈部清扫的患者局部复发明显少于其他手术患者(p<0.05)。2) 14例行局部淋巴结清扫的患者中有11例(73%)在切除区域出现淋巴结复发。15例行改良颈部清扫的患者中有10例(67%)在清扫区域外复发。3) 在高分化癌中,8例行局部淋巴结清扫的患者中有5例(62%)复发,13例行改良颈部清扫的患者中有4例(31%)复发。相比之下,在低分化癌中,我们分别在9例中的8例(89%)和10例中的10例(100%)中发现复发。然而,仅1例行扩大颈部清扫的患者(20%)出现复发。我们得出结论,只要可行,扩大颈部清扫应是复发性甲状腺癌患者的首选手术方式。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验