Koulouvaris Panagiotis, Sculco Peter, Finerty Eileen, Sculco Thomas, Sharrock Nigel E
Policlinic, Olympic Village, Athens, Greece.
Clin Orthop Relat Res. 2009 Jul;467(7):1859-67. doi: 10.1007/s11999-008-0614-8. Epub 2008 Nov 14.
Surgical wound infection is a serious and potentially catastrophic complication after joint arthroplasty. Urinary tract infection is a common infection that creates a potential reservoir of resistant pathogens and increases patient morbidity. We asked whether treated preoperative and postoperative urinary tract infections are risk factors for deep joint infection. We examined the medical records of 19,735 patients. The minimum had joint infections develop. Of these, three had preoperative and four had postoperative urinary tract infections. The majority of bacteria were not enteric. The bacteria in the two types of infections were not identical. Control subjects were randomly selected from a list of patients matched with patients having infections. Of these, eight had preoperative and one had postoperative urinary tract infections. We found no association between the preoperative urinary tract infection (odds ratio, 0.341; 95% confidence interval, 0.086-1.357) or postoperative urinary tract infection (odds ratio, 4.222; 95% confidence interval, 0.457-38.9) and wound infection. Only one of the 58 patients with wound infections had a urinary tract infection with the same bacteria in both infections. Given the infection rate was very low (0.29%), the power of the study was only 25%. Although limited, the data suggest patients with urinary tract infections had no more likelihood of postoperative infection. We believe treated urinary tract infection should not be a reason to delay or postpone surgery.
Level III, therapeutic study.
手术伤口感染是关节置换术后一种严重且可能带来灾难性后果的并发症。尿路感染是一种常见感染,它会形成耐药病原体的潜在储存库并增加患者发病率。我们研究了术前和术后接受治疗的尿路感染是否为深部关节感染的危险因素。我们检查了19735例患者的病历。其中极少发生关节感染。在这些患者中,3例有术前尿路感染,4例有术后尿路感染。大多数细菌并非肠道细菌。两种感染中的细菌并不相同。对照对象是从与感染患者匹配的患者名单中随机选取的。其中,8例有术前尿路感染,1例有术后尿路感染。我们发现术前尿路感染(比值比,0.341;95%置信区间,0.086 - 1.357)或术后尿路感染(比值比,4.222;95%置信区间,0.457 - 38.9)与伤口感染之间无关联。58例伤口感染患者中只有1例在两种感染中感染的是相同细菌。鉴于感染率非常低(0.29%),该研究的检验效能仅为25%。尽管数据有限,但表明尿路感染患者术后感染的可能性并不更高。我们认为接受治疗的尿路感染不应成为延迟或推迟手术的理由。
III级,治疗性研究。