Horvath T J, Schindler A E
Fortschr Med. 1977 Feb 10;95(6):358-60.
The effect on prognosis of the presence of ovarian metastases was studied in patients oophorectomized in treatment of progressive breast cancer. At laparotomy, 28% (n = 42) were found to have ovarian metastases. This high percentage indicates that cases studied were in a relatively progressed state. In the cases with ovarian metastases, the clinical course of the disease was no different to those histologically free from metastases. It appears therefore that the presence of secondary ovarian metastases at oophorectomy is of no therapeutic or prognostic significance. The time interval between oophorectomy and mastectomy, however, apparently does have a bearing on the progress of the disease.
在因进展期乳腺癌接受卵巢切除术的患者中,研究了卵巢转移瘤的存在对预后的影响。在剖腹手术中,发现28%(n = 42)的患者有卵巢转移。如此高的比例表明所研究的病例处于相对进展期。在有卵巢转移的病例中,疾病的临床进程与组织学上无转移的病例并无不同。因此,卵巢切除术中出现继发性卵巢转移对治疗或预后并无意义。然而,卵巢切除术与乳房切除术之间的时间间隔显然与疾病进展有关。