Katz Gregory, Durst Rimona, Shufman Emi, Bar-Hamburger Rachel, Grunhaus Leon
Jerusalem Mental Health Center, Jerusalem, Israel
Isr Med Assoc J. 2008 Oct;10(10):672-5.
The co-morbidity rate of illicit substance abuse and major mental problems in Israel is far from clear.
To investigate the extent of drug abuse in a sample of psychiatric patients hospitalized in a psychiatric hospital and in the psychiatric department of a general hospital in Israel, to compare demographic and other background factors in dual-diagnosis patients with those of abuse-free mental inpatients, and to examine the time correlation between drug abuse and the appearance of major mental problems.
Our data were derived from self-report and urine tests. The study population comprised 470 consecutively admitted patients--250 patients in the mental health center and 220 patients in the psychiatric department of the general hospital.
The lifetime prevalence of drug abuse was 24%; cannabis abuse was found in 19.7%, opiates in 5.7%, cocaine in 2.7%, amphetamines in 3.4% and methamphetamine in 1.1%. Active abuse of drugs (during the last month) was registered in 17.3%, cannabis in 11.5%, opiates in 4.9%, amphetamine in 3.8%, cocaine in 1.3% and methamphetamine in 1.1%. We also found that 28.2% of active abusers used two or more substances. In 41.6% the drug abuse appeared prior to symptoms of the mental disorder; in 37.1% the duration of the mental disorders and the drug abuse was relatively similar, and in 21.3% of cases the duration of mental problems was longer than the duration of drug abuse. Dual-diagnosis patients were younger than non-abusers, more often male, unmarried, and of western origin.
Substance abuse (especially cannabis) among hospitalized psychiatric patients in Israel is a growing problem.
以色列非法药物滥用与严重精神问题的共病率尚不清楚。
调查以色列一家精神病院和一家综合医院精神科住院的精神病患者样本中的药物滥用程度，比较双重诊断患者与无药物滥用的精神科住院患者的人口统计学及其他背景因素，并研究药物滥用与严重精神问题出现之间的时间相关性。
我们的数据来自自我报告和尿液检测。研究人群包括470名连续入院的患者——250名来自心理健康中心，220名来自综合医院精神科。
药物滥用的终生患病率为24%；发现大麻滥用率为19.7%，阿片类药物为5.7%，可卡因为2.7%，苯丙胺为3.4%，甲基苯丙胺为1.1%。（过去一个月内）当前药物滥用率为17.3%，大麻为11.5%，阿片类药物为4.9%，苯丙胺为3.8%，可卡因为1.3%，甲基苯丙胺为1.1%。我们还发现，28.2%的当前滥用者使用两种或更多种物质。在41.6%的病例中，药物滥用先于精神障碍症状出现；在37.1%的病例中，精神障碍和药物滥用的持续时间相对相似，在21.3%的病例中，精神问题的持续时间长于药物滥用的持续时间。双重诊断患者比非滥用者年轻，男性、未婚和西方血统者更为常见。
以色列住院精神病患者中的药物滥用（尤其是大麻滥用）问题日益严重。
