Coulthard E, Rudd A, Husain M
Institute of Neurology and National Hospital for Neurology and Neurosurgery, 17 Queen Square, London WC1N3AR, UK.
J Neurol Neurosurg Psychiatry. 2008 Dec;79(12):1401-4. doi: 10.1136/jnnp.2007.140715.
Motor neglect, underuse of one side of the body not explained by weakness or sensory impairment, is a common consequence of stroke that is surprisingly little understood. Behavioural and neuroanatomical hallmarks of the disorder are investigated. Using a masked prime task, it was shown that when patients with left motor neglect plan to move their left hand, irrelevant right limb motor programmes intrude, causing delay. Lesion analysis reveals that such asymmetry of motor programming occurs after infarcts of the right putamen and motor association areas. This demonstration of failure to inhibit ipsilesional limb motor plans suggests potential benefit from interventions that might act to restore balance in action planning.
肢体运动忽视，即身体一侧未因无力或感觉障碍而出现的使用不足，是中风的常见后果，但令人惊讶的是，人们对此了解甚少。本文对该疾病的行为和神经解剖学特征进行了研究。通过一项掩蔽启动任务发现，当患有左侧肢体运动忽视的患者计划移动其左手时，无关的右侧肢体运动程序会侵入，导致动作延迟。病灶分析表明，这种运动编程的不对称发生在右侧壳核和运动联合区梗死之后。这种无法抑制同侧肢体运动计划的表现表明，可能从有助于恢复动作计划平衡的干预措施中获益。
