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[严重颅脑损伤的后遗症。圣加仑州的一项流行病学研究]

[Sequelae of severe craniocerebral injuries. An epidemiological study in the Canton of St. Gallen].

作者信息

Annoni J M, Beer S, Kesselring J

机构信息

Neurologische Abteilung, Rheuma- und Rehabilitationszentrum, Klinik Valens.

出版信息

Schweiz Med Wochenschr. 1991 Feb 16;121(7):207-13.

PMID:1901176
Abstract

Severe head injuries often lead to serious medical and socioeconomic sequelae. The incidence rate indicated in other studies shows a wide variation due to differences in selection criteria. Based upon an unselected population, the incidence of severe head injury was calculated and the surviving patients were interviewed and clinically examined 3 years after the accident in order to describe the course, rehabilitation and psychosocial sequelae after severe head injury. Retrospectively we collected 80 patients living in the canton of St. Gallen who had a severe head injury requiring hospitalization in 1987, indicating an incidence of 20 per 100,000 inhabitants. 22 (28%) of these patients died as a consequence of the head trauma. The best predictor was the Glasgow coma score at admission, which showed a highly significant direct correlation with survival rate. Regarding the degree of impairment of survivors the duration of posttraumatic amnesia was the best predictive parameter. Of the 45 patients controlled 3 years after the head trauma only 11% were severely impaired in daily activities. 79% of the patients who were gainfully employed before the accident were working full- or at least part-time. However, only 3 patients (7%) were absolutely free of symptoms. Most patients suffered from cognitive and emotional deficits. Based on an estimated incidence for minor head trauma of 174 per 100,000 inhabitants, a total annual incidence for all head traumas of 194 per 100,000 inhabitants is calculated, with severe head injury representing about 1/9 of all head injuries.

摘要

严重颅脑损伤常导致严重的医学和社会经济后遗症。其他研究表明的发病率因选择标准的差异而有很大变化。基于未经过筛选的人群,计算了严重颅脑损伤的发病率,并在事故发生3年后对幸存患者进行了访谈和临床检查,以描述严重颅脑损伤后的病程、康复情况及社会心理后遗症。我们回顾性收集了80例居住在圣加仑州的患者,他们在1987年因严重颅脑损伤而住院,发病率为每10万居民中有20例。其中22例(28%)患者因颅脑外伤死亡。最佳预测指标是入院时的格拉斯哥昏迷评分,它与生存率呈高度显著的正相关。就幸存者的损伤程度而言,创伤后遗忘症的持续时间是最佳预测参数。在颅脑外伤3年后接受检查的45例患者中,只有11%在日常活动中严重受损。事故前有工作的患者中,79%全职或至少兼职工作。然而,只有3例患者(7%)完全没有症状。大多数患者存在认知和情感缺陷。根据估计的每10万居民中轻度颅脑外伤发病率为174例,计算出所有颅脑外伤的年总发病率为每10万居民中有194例,其中严重颅脑损伤约占所有颅脑损伤的1/9。

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