Canullo Luigi, Malagnino Vito Antonio
Int J Oral Maxillofac Implants. 2008 Sep-Oct;23(5):858-66.
The objective of the present study was to clinically and histologically evaluate the effectiveness of deproteinized bovine bone as the augmentation material in vertical ridge augmentation of the inserted implants.
This retrospective study was performed on 10 vertically augmented ridges in which 24 dental implants were inserted. Deproteinized bovine bone (Bio-Oss) was used as the only augmentation material and was covered with a titanium-reinforced expanded polytetrafluoroethylene (e-PTFE) membrane (Gore-Tex). For 3 augmented areas, bone samples were retrieved for histologic and histomorphometric examination.
Clinical evaluations showed bone defects around the implants of 2 to 9 mm (average -5.1 mm; SD = 2.1). Bone height gain at 6 to 8 months after augmentation was 3 to 9 mm (average 5.3 mm; SD = 1.7). Differences between pre- and postaugmentation were statistically significant, for a mean value of > 4 mm (P < .005). The obtained bone biopsy specimens showed significant new bone formation and remodeling of the deproteinized bovine bone material. The radiographic data and the clinical stability showed that all implants were successfully osseointegrated. The radiographic and clinical follow-up indicated that the generated bone crest levels were stable.
This clinical study suggests that vertical ridge augmentation with an e-PTFE membrane and deproteinized bovine bone is predictable and can lead to long-term success.
本研究的目的是从临床和组织学角度评估脱蛋白牛骨作为植入种植体垂直牙槽嵴增高术的增高材料的有效性。
本回顾性研究针对10个垂直增高的牙槽嵴进行，其中植入了24颗牙种植体。脱蛋白牛骨（Bio-Oss）被用作唯一的增高材料，并覆盖有钛增强型膨体聚四氟乙烯（e-PTFE）膜（Gore-Tex）。对于3个增高区域，获取骨样本进行组织学和组织形态计量学检查。
临床评估显示种植体周围的骨缺损为2至9毫米（平均-5.1毫米；标准差=2.1）。增高后6至8个月的骨高度增加为3至9毫米（平均5.3毫米；标准差=1.7）。增高前后的差异具有统计学意义，平均值>4毫米（P<.005）。获得的骨活检标本显示脱蛋白牛骨材料有显著的新骨形成和重塑。影像学数据和临床稳定性表明所有种植体均成功实现骨整合。影像学和临床随访表明所形成的牙槽嵴水平稳定。
这项临床研究表明，使用e-PTFE膜和脱蛋白牛骨进行垂直牙槽嵴增高术是可预测的，并且可以带来长期成功。
