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经骶骨结肠瘘:骶骨软骨肉瘤切除、放疗及游离皮瓣转移后的晚期并发症。

Transsacral colon fistula: late complication after resection, irradiation and free flap transfer of sacral chondrosarcoma.

作者信息

Steinstraesser Lars, Sand Michael, Langer Stefan, Muhr Gert, Schildhauer Thomas A, Steinau Hans-Ulrich

机构信息

Department of Plastic Surgery, Burn Center, Ruhr-University Bochum, Bergmannsheil, Bochum, Germany.

出版信息

World J Surg Oncol. 2008 Nov 11;6:121. doi: 10.1186/1477-7819-6-121.

DOI:10.1186/1477-7819-6-121
PMID:19014448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2587464/
Abstract

BACKGROUND

Primary sacral tumors are rare and experience related to accompanying effects of these tumors is therefore limited to observations on a small number of patients.

CASE PRESENTATION

In this case report we present a patient with a history of primary sacral chondrosarcoma, an infection of an implanted spinal stabilization device and discuss the challenges that resulted from a colonic fistula associated with large, life threatening abscesses as late complications of radiotherapy.

CONCLUSION

In patients with sacral tumors enterocutaneous fistulas after free musculotaneous free flaps transfer are rare and can occur in the setting of surgical damage followed by radiotherapy or advanced disease. They are associated with prolonged morbidity and high mortality. Identification of high-risk patients and management of fistulas at an early stage may delay the need for subsequent therapy and decrease morbidity.

摘要

背景

原发性骶骨肿瘤罕见,因此关于这些肿瘤伴随影响的经验仅限于对少数患者的观察。

病例报告

在本病例报告中,我们介绍了一名有原发性骶骨软骨肉瘤病史、植入的脊柱稳定装置感染的患者,并讨论了作为放疗晚期并发症的与巨大、危及生命的脓肿相关的结肠瘘所带来的挑战。

结论

在骶骨肿瘤患者中,游离肌皮瓣转移术后肠皮肤瘘罕见,可发生在手术损伤后继发放疗或晚期疾病的情况下。它们与延长的发病率和高死亡率相关。识别高危患者并早期处理瘘管可能会延迟后续治疗的需求并降低发病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/e2dbd3d05069/1477-7819-6-121-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/98ba7a6670e8/1477-7819-6-121-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/c86ce63f9eba/1477-7819-6-121-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/85999f36b20e/1477-7819-6-121-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/edba8be0fc73/1477-7819-6-121-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/56d6a2dfd305/1477-7819-6-121-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/e2dbd3d05069/1477-7819-6-121-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/98ba7a6670e8/1477-7819-6-121-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/c86ce63f9eba/1477-7819-6-121-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/85999f36b20e/1477-7819-6-121-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/edba8be0fc73/1477-7819-6-121-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/56d6a2dfd305/1477-7819-6-121-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d42/2587464/e2dbd3d05069/1477-7819-6-121-6.jpg

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Ann Plast Surg. 2006 Nov;57(5):521-8. doi: 10.1097/01.sap.0000226931.23076.a7.
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Combined radiotherapy and razoxane in the treatment of chondrosarcomas and chordomas.联合放疗与丙亚胺治疗软骨肉瘤和脊索瘤。
Anticancer Res. 2006 May-Jun;26(3B):2407-11.
3
Sarcoma and skin radiation oncology.肉瘤与皮肤放射肿瘤学
Hematol Oncol Clin North Am. 2006 Apr;20(2):401-29. doi: 10.1016/j.hoc.2006.01.017.
4
Sacral resection and reconstruction for tumors and tumor-like conditions.用于肿瘤及肿瘤样病变的骶骨切除术及重建术。
Orthopedics. 2005 Mar;28(3):307-13. doi: 10.3928/0147-7447-20050301-17.
5
Benign sacral tumors.良性骶骨肿瘤
Neurosurg Focus. 2003 Aug 15;15(2):E14. doi: 10.3171/foc.2003.15.2.14.
6
Giant cell tumor of the sacrum.骶骨巨细胞瘤
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Osteoid osteoma and osteoblastoma of the sacrum.骶骨骨样骨瘤和成骨细胞瘤
Orthopedics. 2001 Nov;24(11):1061-4. doi: 10.3928/0147-7447-20011101-16.
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Prognostic factors and outcome of pelvic, sacral, and spinal chondrosarcomas: a center-based study of 69 cases.骨盆、骶骨和脊柱软骨肉瘤的预后因素及结果:一项基于中心的69例病例研究
Cancer. 2001 Apr 1;91(7):1201-12. doi: 10.1002/1097-0142(20010401)91:7<1201::aid-cncr1120>3.0.co;2-w.
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Primary bone tumors and pseudotumors of the lumbosacral spine.腰骶椎原发性骨肿瘤和肿瘤样病变
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Am Surg. 1998 Dec;64(12):1204-11.