阿斯伯格综合征与双相情感障碍的共病情况。
Comorbidity of Asperger's syndrome and Bipolar disorder.
作者信息
Raja Michele, Azzoni Antonella
机构信息
Servizio Psichiatrico di Diagnosi e Cura, Ospedale Santo Spirito in Sassia, Rome, Italy.
出版信息
Clin Pract Epidemiol Ment Health. 2008 Nov 17;4:26. doi: 10.1186/1745-0179-4-26.
BACKGROUND AND OBJECTIVE
Asperger's Syndrome (AS) is a pervasive developmental disorder that is sometimes unrecognized, especially in the adult psychiatric setting. On the other hand, in patients with an AS diagnosis, comorbid psychiatric disorders may be unrecognized in the juvenile setting. The aim of the paper is to show and discuss some troublesome and complex problems of the management of patients with AS and comorbid Bipolar Disorder (BD).
METHODS
The paper describes three patients affected by AS and bipolar spectrum disorders.
RESULTS AND CONCLUSION
Mood stabilizers and 2nd generation antipsychotics were effective in the treatment of these AS patients with comorbid BD, while the use of antidepressants was associated with worsening of the mood disorder.It is of importance to recognize both the psychiatric diagnoses in order to arrange an exhaustive therapeutic program and to define specific and realistic goals of treatment.
背景与目的
阿斯伯格综合征（AS）是一种广泛性发育障碍，有时难以识别，尤其是在成人精神科环境中。另一方面，在已诊断为AS的患者中，共病的精神障碍在青少年环境中可能未被识别。本文旨在展示和讨论AS合并双相情感障碍（BD）患者管理中一些棘手和复杂的问题。
方法
本文描述了3例患有AS和双相谱系障碍的患者。
结果与结论
心境稳定剂和第二代抗精神病药物对这些合并BD的AS患者治疗有效，而使用抗抑郁药与心境障碍恶化相关。识别这两种精神科诊断对于安排详尽的治疗方案以及确定具体且现实的治疗目标非常重要。
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