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自闭症儿童的共病精神障碍:访谈开发与障碍发生率

Comorbid psychiatric disorders in children with autism: interview development and rates of disorders.

作者信息

Leyfer Ovsanna T, Folstein Susan E, Bacalman Susan, Davis Naomi O, Dinh Elena, Morgan Jubel, Tager-Flusberg Helen, Lainhart Janet E

机构信息

Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY, USA.

出版信息

J Autism Dev Disord. 2006 Oct;36(7):849-61. doi: 10.1007/s10803-006-0123-0.

Abstract

The Kiddie Schedule for Affective Disorders and Schizophrenia was modified for use in children and adolescents with autism by developing additional screening questions and coding options that reflect the presentation of psychiatric disorders in autism spectrum disorders. The modified instrument, the Autism Comorbidity Interview-Present and Lifetime Version (ACI-PL), was piloted and frequently diagnosed disorders, depression, ADHD, and OCD, were tested for reliability and validity. The ACI-PL provides reliable DSM diagnoses that are valid based on clinical psychiatric diagnosis and treatment history. The sample demonstrated a high prevalence of specific phobia, obsessive compulsive disorder, and ADHD. The rates of psychiatric disorder in autism are high and are associated with functional impairment.

摘要

《儿童情感障碍与精神分裂症量表》针对患有自闭症的儿童和青少年进行了修改,通过开发额外的筛查问题和编码选项,以反映自闭症谱系障碍中精神疾病的表现。修改后的工具《自闭症共病访谈-当前和终生版》(ACI-PL)进行了试点,并对常见诊断的疾病、抑郁症、注意力缺陷多动障碍(ADHD)和强迫症进行了信效度测试。ACI-PL基于临床精神科诊断和治疗史,提供可靠的《精神疾病诊断与统计手册》(DSM)诊断。样本显示特定恐惧症、强迫症和ADHD的患病率很高。自闭症患者中精神疾病的发生率很高,且与功能损害相关。

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