Seneviratne Deepthi Renuka, Mollan Susan P, Elsherbiny Samer, Worstmann Theresa
Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.
J Med Case Rep. 2008 Nov 17;2:346. doi: 10.1186/1752-1947-2-346.
We describe a case of giant cell arteritis in a woman who was treated with high-dose systemic corticosteroids and subsequently developed acute pancreatitis.
A 78-year-old Caucasian woman presented with four weeks of progressive headache and scalp tenderness. One day before ophthalmology assessment, she had experienced visual obscurations in both eyes. Her visual acuity was 6/9 in both eyes, with a right afferent pupillary defect and right swollen optic nerve. She was diagnosed as having temporal arteritis and was urgently treated with high-dose pulsed intravenous and oral corticosteroids. Her previous diet-controlled diabetes needed insulin and oral hyperglycaemic therapy to control erratic blood sugars. On day 8 of treatment with steroids, she became unwell with epigastric pain and vomiting. She was diagnosed with acute pancreatitis and was treated conservatively.
Acute pancreatitis, a potentially life-threatening condition, is a rare but important side effect of systemic corticosteroids.
我们描述了一例巨细胞动脉炎女性患者,该患者接受了大剂量全身糖皮质激素治疗,随后发生了急性胰腺炎。
一名78岁的白种女性,出现进行性头痛和头皮压痛四周。在眼科评估前一天,她双眼出现视力模糊。双眼视力均为6/9,右侧存在传入性瞳孔障碍和右侧视神经肿胀。她被诊断为颞动脉炎,并紧急接受了大剂量静脉脉冲和口服糖皮质激素治疗。她之前通过饮食控制的糖尿病现在需要胰岛素和口服降糖药来控制不稳定的血糖。在使用类固醇治疗的第8天,她出现上腹部疼痛和呕吐不适。她被诊断为急性胰腺炎,并接受了保守治疗。
急性胰腺炎是一种潜在的危及生命的疾病,是全身糖皮质激素罕见但重要的副作用。