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[Glucagonoma syndrome without diabetes mellitus].

作者信息

Mikkelsen Carsten Sauer, Mikkelsen Dorthe Bisgaard, Vestergaard Vibeke, Clemmensen Ole, Nielsen Henning Overgaard, Bygum Anette

机构信息

Odense Universitetshospital, Afdeling for Klinisk Patologi, Odense C.

出版信息

Ugeskr Laeger. 2008 Nov 17;170(47):3876.

PMID:19014744
Abstract

A patient developed depression, weight loss, ulcers and a migrating, denuded erythematous skin area. Punch biopsy revealed necrolytic migrating erythema. Computerised tomography and endoscopic ultrasound showed a solid tumour of the pancreas. A blood sample showed an increased level of glucagon without diabetes. Glucagonoma syndrome is characterized by glucagon overproduction, diabetes, depression, deep venous thrombosis and necrolytic migrating erythema. Glucagonoma is frequently diagnosed late which increases the risk of metastases. It is important not to rule out glucagonoma in patients with a relevant clinical picture but without diabetes.

摘要

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1
[Glucagonoma syndrome without diabetes mellitus].
Ugeskr Laeger. 2008 Nov 17;170(47):3876.
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