Neau J P, Guilhot F, Dumas P, Besson I, Rivasseau-Jonveaux T, Gil R
Clinique Neurologique, CHU Poitiers.
Rev Neurol (Paris). 1991;147(1):56-60.
Three cases of central nervous system involvement in Waldenström's macroglobulinemia (Bing Neel's syndrome) are reported. Such cases are unusual and have a poor prognosis. One patient received chemotherapy including BCNU, cyclophosphamide, vincristine, melphalan and prednisolone, which was followed by a dramatic improvement. The pathogenesis of Bing Neel's syndrome is discussed.
报告了3例华氏巨球蛋白血症(宾-尼尔综合征)累及中枢神经系统的病例。此类病例较为罕见,预后较差。1例患者接受了包括卡氮芥、环磷酰胺、长春新碱、美法仑和泼尼松龙在内的化疗,随后病情显著改善。文中讨论了宾-尼尔综合征的发病机制。