Federman D G, Shelling M, Prodanovich S, Gunderson C G, Kirsner R S
Department of Medicine, VA Connecticut Health Care Center (11ACSL), 950 Campbell Ave., West Haven, CT 06516, USA.
Br J Dermatol. 2009 Jan;160(1):1-7. doi: 10.1111/j.1365-2133.2008.08874.x. Epub 2008 Oct 25.
Psoriasis is highly prevalent and is associated with skin-associated complaints as well as arthritis, depression and a lower quality of life. Recently, it has been demonstrated that not only do patients with psoriasis have an increased prevalence of cardiovascular risk factors, but an increased risk of myocardial infarction, and for those with severe disease, increased mortality. Dermatologists and other health professionals need to be cognizant of this association and ensure that cardiovascular risk factors are evaluated and treated appropriately in those patients with psoriasis. We review the association between psoriasis, atherosclerosis and inflammation, as well as some treatable cardiovascular risk factors that may prove beneficial in reducing a patient's cardiovascular risk.
银屑病非常普遍,与皮肤相关症状以及关节炎、抑郁症和较低的生活质量有关。最近有研究表明,银屑病患者不仅心血管危险因素的患病率增加,心肌梗死风险也增加,对于重症患者,死亡率也会升高。皮肤科医生和其他医疗专业人员需要认识到这种关联,并确保对银屑病患者的心血管危险因素进行适当评估和治疗。我们将综述银屑病、动脉粥样硬化与炎症之间的关联,以及一些可能有助于降低患者心血管风险的可治疗的心血管危险因素。