Tufts Medical Center, Boston, Mass., USA.
Am J Med. 2009 Dec;122(12):1150.e1-9. doi: 10.1016/j.amjmed.2009.06.021.
Psoriasis is a common chronic inflammatory disease that is associated with serious comorbidities, including psoriatic arthritis, reduced quality of life, depression, malignancy, and cardiovascular comorbidities. Patients with psoriasis have been shown to have an increased incidence of metabolic syndrome and cardiovascular disease compared with the general population. The chronic inflammatory nature of psoriasis has been suggested to be a contributing and potentially independent risk factor for the development of cardiovascular comorbidities. Understanding the interrelationship between these conditions is important for the management of psoriasis and the associated comorbidities. This review will focus on the range of comorbidities associated with psoriasis, with emphasis on cardiometabolic conditions and the aim of encouraging primary care physicians to screen psoriatic patients for cardiometabolic disorders and risk factors.
银屑病是一种常见的慢性炎症性疾病，与严重的合并症有关，包括银屑病关节炎、生活质量降低、抑郁、恶性肿瘤和心血管合并症。与一般人群相比，银屑病患者的代谢综合征和心血管疾病发病率增加。银屑病的慢性炎症性质被认为是心血管合并症发展的一个促成因素和潜在的独立危险因素。了解这些疾病之间的相互关系对于银屑病及其相关合并症的管理很重要。本综述将重点介绍与银屑病相关的一系列合并症，强调心血管代谢疾病，并旨在鼓励初级保健医生为银屑病患者筛查心血管代谢疾病和危险因素。
