Tong L C B, Kamil Z S, Al Habeeb A, Ghazarian D
Department of Laboratory Medicine and Pathobiology, University of Toronto and University Health Network, Ontario, Canada.
J Clin Pathol. 2009 Apr;62(4):290-307. doi: 10.1136/jcp.2008.062927. Epub 2008 Nov 18.
Intradermal melanoma diagnosis poses a great deal of confusion on many occasions since it can mimic almost any tumour within the dermis. In part I, the different features of intraepidermal mimics were discussed. In this part, there is discussion of the clinical, cytomorphological and immunohistochemical features of intradermal mimics of melanoma and how to distinguish these conditions from melanoma. There is also a description of the ultrastructural features of some of these conditions that may help to distinguish melanoma from its mimics. It is hoped that this approach, together with part I of the non-melanocytic mimics of melanoma, will aid in better overall understanding of melanoma and its mimics.
皮内黑色素瘤的诊断在很多情况下会造成极大的混淆,因为它几乎可以模仿真皮内的任何肿瘤。在第一部分中,讨论了表皮内模仿物的不同特征。在这一部分中,将讨论黑色素瘤皮内模仿物的临床、细胞形态学和免疫组化特征,以及如何将这些情况与黑色素瘤区分开来。还描述了其中一些情况的超微结构特征,这些特征可能有助于将黑色素瘤与其模仿物区分开来。希望这种方法,连同黑色素瘤的非黑素细胞模仿物的第一部分,将有助于更好地全面理解黑色素瘤及其模仿物。