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接受化疗的乳腺癌患者生活质量的预测因素。

Predictors of quality of life in breast cancer patients under chemotherapy.

作者信息

Safaee A, Moghimi-Dehkordi B, Zeighami B, Tabatabaee Hr, Pourhoseingholi Ma

机构信息

Department of HSR, Research Center of Gastroenterology and Liver Diseases, Shahid Beheshti University (MC), Tehran, Iran.

出版信息

Indian J Cancer. 2008 Jul-Sep;45(3):107-11. doi: 10.4103/0019-509x.44066.

Abstract

BACKGROUND

Today, the quality of life studies has an important role in health care especially in chronic diseases. Breast cancer has third order among women's malignancies. Now, survival rate for this cancer is long. However breast cancer has several complications that affected the patient's life.

AIMS

The aim of this study was to assess the quality of life in Breast cancer patients under chemotherapy.

SETTING AND DESIGN

A cross-sectional study conducted on 119 breast cancer patients that were admitted and treated in chemotherapy ward of Namazi hospital in Shiraz city, south of Iran, between Jan and Feb 2006.

MATERIALS AND METHODS

The QLQ-C30 questionnaire was used to assess quality of life in these patients.

STATISTICAL ANALYSIS

We used univariate methods. A multiple regression analysis was performed to identify predictors of quality of life.

RESULTS

Mean age of patients was 48.27+/-11.42 with quality of life total score 64.92+/-24.28. All symptoms scales had reverse association with quality of life except appetite loss (P>0.05) and diarrhea (P=0.752). The results of the regression analyses showed that only grade of tumor, occupational status, menopausal status, financial difficulties and dyspnea were statistically significant in predicting patients' quality of life.

CONCLUSION

In conclusion, this study demonstrates the strength of the relationship between clinical and sociodemographical factors and breast cancer patients' quality of life. Psychological and financial support for women experiencing breast cancer diagnosis may improve quality of life.

摘要

背景

如今,生活质量研究在医疗保健中,尤其是在慢性病领域发挥着重要作用。乳腺癌在女性恶性肿瘤中位列第三。目前,这种癌症的生存率较高。然而,乳腺癌存在多种并发症,会影响患者的生活。

目的

本研究旨在评估接受化疗的乳腺癌患者的生活质量。

设置与设计

2006年1月至2月间,在伊朗南部设拉子市纳马齐医院化疗病房对119名入院接受治疗的乳腺癌患者进行了一项横断面研究。

材料与方法

使用QLQ-C30问卷评估这些患者的生活质量。

统计分析

采用单变量方法。进行多元回归分析以确定生活质量的预测因素。

结果

患者的平均年龄为48.27±11.42岁,生活质量总分64.92±24.28。除食欲减退(P>0.05)和腹泻(P=0.752)外,所有症状量表与生活质量呈负相关。回归分析结果显示,仅肿瘤分级、职业状况、绝经状态、经济困难和呼吸困难在预测患者生活质量方面具有统计学意义。

结论

总之,本研究证明了临床和社会人口学因素与乳腺癌患者生活质量之间关系的强度。为确诊乳腺癌的女性提供心理和经济支持可能会改善生活质量。

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