Inoue Maiko, Watanabe Yoichiro, Arakawa Akira, Sato Shimpei, Kobayashi Satoshi, Kadonosono Kazuaki
Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan.
Graefes Arch Clin Exp Ophthalmol. 2009 Mar;247(3):325-30. doi: 10.1007/s00417-008-0999-9. Epub 2008 Nov 19.
To evaluate the ability of spectral-domain optical coherence tomography (SD-OCT) images of the inner/outer segment (IS/OS) junction to predict macular hole surgery outcomes.
Fifty-four eyes in 53 patients with idiopathic macular holes were studied. Postoperative visual acuity and SD-OCT images of the fovea were examined before and 12 months after surgery. The total area and the maximum length of the IS/OS junction defect were measured.
The macular holes were successfully closed in all the eyes included in this series. The mean log MAR visual acuity improved significantly from 0.67 +/- 0.25 preoperatively to 0.16 +/- 0.22 postoperatively (p < 0.001). The mean total area and maximum length of the IS/OS junction defect at 12 months after surgery were 10,185 +/- 1,537 microm(2) and 100.5 +/- 10.4 microm respectively; these values were significantly negatively correlated with the postoperative visual acuity.
SD-OCT is useful for quantitatively measuring IS/OS junction defects. The postoperative IS/OS junction may play an important role in visual recovery after macular hole surgery.
评估内/外节（IS/OS）交界处的频域光学相干断层扫描（SD-OCT）图像预测黄斑裂孔手术结果的能力。
对53例特发性黄斑裂孔患者的54只眼进行研究。在手术前和手术后12个月检查中心凹的术后视力和SD-OCT图像。测量IS/OS交界处缺损的总面积和最大长度。
本系列所有眼中的黄斑裂孔均成功封闭。平均对数最小分辨角视力从术前的0.67±0.25显著提高到术后的0.16±0.22（p<0.001）。术后12个月时，IS/OS交界处缺损的平均总面积和最大长度分别为10,185±1,537平方微米和100.5±10.4微米；这些值与术后视力显著负相关。
SD-OCT可用于定量测量IS/OS交界处缺损。术后IS/OS交界处可能在黄斑裂孔手术后的视力恢复中起重要作用。
