Kocaeli University Faculty of Medicine, Department of Ophthalmology, Kocaeli, Turkey.
Dünyagöz Kocaeli Hospital, Clinic of Ophthalmology, Kocaeli, Turkey.
Turk J Ophthalmol. 2020 Oct 30;50(5):283-287. doi: 10.4274/tjo.galenos.2020.21456.
To assess changes in reflectivity of the retinal pigment epithelium (RPE), ellipsoid zone (EZ), and external limiting membrane (ELM) on spectral domain-optical coherence tomography (SD-OCT) images and the effects of reflectivity changes on visual acuity improvement after vitrectomy in macular hole patients.
Twenty-four eyes of 24 patients with idiopathic full-thickness macular hole closed after vitrectomy were retrospectively reviewed. The "plot profile" function of the medical imaging software was used by a single masked physician to analyze RPE, EZ, and ELM reflectivity on OCT images at postoperative 1 month and 12 months.
Absolute and relative EZ reflectivity showed highly significant increases at postoperative 12 months compared to 1 month (p<0.001 and p<0.001, respectively). Absolute and relative EZ reflectivity changes from postoperative month 1 to month 12 after macular hole surgery were significantly correlated with best corrected visual acuity improvement (p=0.012 and p=0.020, respectively).
EZ reflectivity can be a predictor of functional and anatomical improvement after macular hole surgery.
评估特发性全层黄斑孔手术后玻璃体内切除术后视网膜色素上皮(RPE)、椭圆体带(EZ)和外界膜(ELM)的反射率变化,以及反射率变化对黄斑孔患者视力提高的影响。
回顾性分析 24 例 24 只眼特发性全层黄斑孔闭合后行玻璃体切除术后的病例。由一名单盲医生使用医学成像软件的“绘图分析”功能,在术后 1 个月和 12 个月分析 OCT 图像上的 RPE、EZ 和 ELM 反射率。
术后 12 个月时 EZ 绝对和相对反射率与术后 1 个月相比显著增加(p<0.001 和 p<0.001)。黄斑孔手术后第 1 个月至第 12 个月时 EZ 绝对和相对反射率的变化与最佳矫正视力的提高显著相关(p=0.012 和 p=0.020)。
EZ 反射率可以预测黄斑孔手术后功能和解剖学的改善。