Das Pranab, Clavijo Leonardo C, Nanjundappa Aravinda, Dieter Robert S
Department of Internal Medicine, Division of Cardiology, University of Tennessee Health Sciences Center, Memphis, TN 38104, USA.
Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1393-6. doi: 10.1586/14779072.6.10.1393.
Carotid artery stenosis is often associated with advanced coronary artery disease. The coexistence of carotid and coronary artery disease adds complexity to the medical decision process and brings increasing challenge to the perioperative management of coronary artery bypass graft (CABG) surgery. Postoperative stroke remains one of the most devastating complications of CABG, thereby contributing to the increased risk of mortality following CABG. Carotid artery disease causes approximately a third of post-CABG stroke and thus needs to be addressed while preparing a patient for CABG. While carotid endarterectomy (CEA) has been the gold standard of carotid artery revascularization, carotid artery stenting may be noninferior to CEA in patients with increased surgical risks. Thus, a consensus as how to best revascularize patients with carotid artery stenosis before CABG is yet to emerge. We have reviewed the current literature and have addressed the pros and cons of the two modalities of carotid artery revascularization. Based on the current literature, the best management strategy for patients with concomitant surgical coronary artery disease in need of CABG and significant carotid artery stenosis should be based on individual patient characteristics, urgency of revascularization, prioritization based on the symptomatic vascular territory, local expertise with an integrated team approach by interventionalists, neurologists and cardiothoracic surgeons, preferably in high-volume centers.
颈动脉狭窄常与晚期冠状动脉疾病相关。颈动脉和冠状动脉疾病并存增加了医疗决策过程的复杂性,给冠状动脉旁路移植术(CABG)的围手术期管理带来了越来越大的挑战。术后卒中仍然是CABG最具毁灭性的并发症之一,从而导致CABG后死亡风险增加。颈动脉疾病约占CABG术后卒中的三分之一,因此在为患者准备CABG时需要解决这一问题。虽然颈动脉内膜切除术(CEA)一直是颈动脉血运重建的金标准,但对于手术风险增加的患者,颈动脉支架置入术可能不劣于CEA。因此,对于如何在CABG前为颈动脉狭窄患者进行最佳血运重建尚未达成共识。我们回顾了当前的文献,并阐述了两种颈动脉血运重建方式的优缺点。基于当前文献,对于需要进行CABG且有严重颈动脉狭窄的合并外科冠状动脉疾病患者,最佳管理策略应基于患者个体特征、血运重建的紧迫性、根据有症状血管区域进行优先排序、介入专家、神经科医生和心胸外科医生采用综合团队方法的当地专业知识,最好是在高容量中心进行。