Hung Chi-Sheng, Lin Jou-Wei, Hwang Juey-Jen, Tsai Ru-Yi, Li Ai-Tzu
Cardiovascular Center, National Taiwan University Hospital Yun-Lin Branch, Dou-Liou City, Yun-Lin, Taiwan.
J Eval Clin Pract. 2008 Oct;14(5):861-6. doi: 10.1111/j.1365-2753.2008.01066.x.
RATIONALE, AIMS AND OBJECTIVES: The objective of this study was to apply a paper-based clinical reminder to improve the adherence to lipid guidelines.
Patients with coronary heart disease (CHD) without lipid-lowering therapy (LLT) were recruited, and medical records were reviewed. Eligible subjects were randomized; a clinical reminder stating current standards and local insurance policy was stamped on the paper chart in the study group but not in the control. The primary outcome was new LLT subscription in the 6-month follow-up period, and the secondary end point was the composite result of LLT or lipid profile check-up.
Ninety-two patients were assigned to the study group and 102 to the control group. The primary outcome showed no difference at the end of 6 months (OR: 1.70, P = 0.248, 95% CI: 0.69-4.19). The secondary end point was significantly higher in the reminder group (OR: 2.81, P = 0.001, 95% CI: 1.57-5.04).
A paper chart based clinical reminder providing update clinical recommendations could modify the doctor's behaviour and improve the attention to lipid levels. However, its effect cannot be transformed into an increase in LLT or a decrease in low-density lipoprotein level owing to local policy constraint.
原理、目的和目标:本研究的目的是应用纸质临床提醒来提高对血脂指南的依从性。
招募未接受降脂治疗(LLT)的冠心病(CHD)患者,并查阅病历。符合条件的受试者被随机分组;研究组在纸质病历上加盖一份说明当前标准和当地保险政策的临床提醒,而对照组则不加盖。主要结局是6个月随访期内新的LLT处方,次要终点是LLT或血脂检查的综合结果。
92例患者被分配到研究组,102例被分配到对照组。6个月末主要结局无差异(比值比:1.70,P = 0.248,95%可信区间:0.69 - 4.19)。提醒组的次要终点显著更高(比值比:2.81,P = 0.001,95%可信区间:1.57 - 5.04)。
基于纸质病历的临床提醒提供最新的临床建议可以改变医生的行为并提高对血脂水平的关注。然而,由于当地政策限制,其效果无法转化为LLT增加或低密度脂蛋白水平降低。