Aissa I, Khaldi H, Yacoub Z, Ayadi-Kadour A, El Mezni F, Capron F, Ghedira H
Service de pneumologie-I, hôpital de pneumo-phtisiologie Abderrahman-Mami, 2080 L'Ariana, Tunis, Tunisie.
Rev Pneumol Clin. 2008 Aug;64(4):173-7. doi: 10.1016/j.pneumo.2008.07.001. Epub 2008 Sep 19.
Epithelioid haemangioendothelioma is a rare vascular tumour of slow growth and unfavourable outcome. The diagnosis of the pulmonary localisation is difficult and can mimic by clinical and radiological features other diagnosis as hypersensitivity pneumonitis. We report the case of a 28-year-old man, farmer handling with palm tree pollens, admitted to the hospital for dry cough. Clinical and thoracic computed tomography findings revealed diffuse infiltrating pneumopathy; bronchoalveolar lavage results and professional exposure were suggestive for hypersensivity pneumonitis. Surgical lung biopsy with immunochemistry study concluded to pulmonary epithelioid haemangioendothelioma. Extra pulmonary localisation research was negative. No treatment was indicated. At three years, the patient is steel asymptomatic. Epithelioid haemangioendothelioma is a tumour of intermediate malignancy, of which pulmonary localisation has a nonspecific clinical presentation mimicking diffuse infiltrating pneumonitis. Diagnosis is essentially made by surgical lung biopsy with pathological and immunohistochemical study.
上皮样血管内皮瘤是一种生长缓慢且预后不良的罕见血管肿瘤。肺部定位的诊断较为困难，其临床和放射学特征可能会与其他疾病如过敏性肺炎相混淆。我们报告了一例28岁男性病例，该患者为农民，接触棕榈树花粉，因干咳入院。临床和胸部计算机断层扫描结果显示弥漫性浸润性肺病；支气管肺泡灌洗结果及职业暴露提示过敏性肺炎。经手术肺活检及免疫化学研究确诊为肺上皮样血管内皮瘤。肺外定位检查为阴性。未给予治疗。三年来，患者仍无症状。上皮样血管内皮瘤是一种中度恶性肿瘤，其肺部定位具有模仿弥漫性浸润性肺炎的非特异性临床表现。诊断主要通过手术肺活检及病理和免疫组织化学研究来确定。
