Jorens P G, Appel B J, Hilte F A, Mahler C, De Deyn P P
Department of Internal Medicine, General Hospital, Middelheim, Antwerp, Belgium.
Acta Neurol Scand. 1991 Feb;83(2):137-40. doi: 10.1111/j.1600-0404.1991.tb04663.x.
A patient is described with post-thyroidectomy hypoparathyroidism and basal ganglia calcifications. The patient presented with a tonic-clonic seizure. The calcifications shown on CT scan were extensive in the basal ganglia, the bifrontal periventricular white matter and even in the brainstem. The white matter with calcifications displayed a high signal intensity on MRI, probably due to a different stage of the calcifying process in the white matter than in the basal ganglia. A severe dystonic reaction was observed after phenothiazine therapy and is discussed.