Eichenbaum Howard, Lipton Paul A
Center for Memory and Brain, Department of Psychology, Boston University, Boston, Massachusetts 02215, USA.
Hippocampus. 2008;18(12):1314-24. doi: 10.1002/hipo.20500.
Whereas substantial recent evidence has suggested to some that the medial entorhinal cortexá (MEC) plays a specialized role in spatial navigation, here we present evidence consistent with a broader role of the MEC in memory. A consideration of evidence on the anatomy and functional roles of medial temporal cortical areas and the hippocampus, and evidence from recordings from MEC neurons in rats performing a spatial memory task, suggest that the MEC may process information about both spatial and temporal context in support of episodic memory.
尽管最近有大量证据向一些人表明，内嗅皮质内侧（MEC）在空间导航中发挥着特殊作用，但在此我们提出的证据表明，MEC在记忆方面具有更广泛的作用。对内颞叶皮质区域和海马体的解剖结构及功能作用的证据进行考量，以及对执行空间记忆任务的大鼠MEC神经元记录所得的证据表明，MEC可能处理有关空间和时间背景的信息，以支持情景记忆。
