Vincelette Rebecca L, Welch Ashley J, Thomas Robert J, Rockwell Benjamin A, Lund David J
University of Texas, Department of Biomedical Engineering, 1 University Station, C0800, Austin, Texas 78712, USA.
J Biomed Opt. 2008 Sep-Oct;13(5):054005. doi: 10.1117/1.2978066.
Ocular damage threshold data remain sparse in the continuous wave (CW), near-infrared (NIR) radiation region save for the 1300-nm area that has been investigated in the past several decades. The 1300-nm ocular damage data have yielded unusual characteristics where CW retinal damage was observed in rabbit models, but never in nonhuman primate models. This paper reviews the existing 1300-nm ocular damage threshold data in terms of the fundamental criteria of an action spectrum to assist in explaining laser-tissue effects from near-infrared radiation in the eye. Reviewing the action spectrum criteria and existing NIR retinal lesion data lend evidence toward the significant presence of thermal lensing in ocular media affecting damage, a relatively unexplored mechanism of laser-tissue interaction.
除了在过去几十年中已被研究的1300纳米区域外，连续波（CW）近红外（NIR）辐射区域的眼部损伤阈值数据仍然稀少。1300纳米的眼部损伤数据呈现出不寻常的特征，即在兔模型中观察到连续波视网膜损伤，但在非人类灵长类动物模型中从未观察到。本文根据作用光谱的基本标准，对现有的1300纳米眼部损伤阈值数据进行了综述，以帮助解释眼睛中近红外辐射的激光-组织效应。回顾作用光谱标准和现有的近红外视网膜病变数据，为眼内介质中影响损伤的热透镜效应的显著存在提供了证据，这是一种相对未被探索的激光-组织相互作用机制。
