Hoffmann R, Bubeck B, Raue F
Abteilung Nuklearmedizin, Medizinische Universitätsklinik Heidelberg.
Dtsch Med Wochenschr. 1991 Apr 26;116(17):654-8. doi: 10.1055/s-2008-1063662.
A 17-year-old female underwent surgical removal of a painless submental lump presumed to be a median cervical cyst. Histology showed a papillary thyroid carcinoma with invasion of the surrounding connective tissue. A 99m-technetium scan, performed in preparation for a planned total thyroidectomy, demonstrated no thyroid tissue. On subsequent 123-iodine scanning there was an area of increased uptake about 3 cm above the larynx, but no normal thyroid tissue. Histological sections, obtained during further surgical exploration of the base of the tongue, showed scattered thyroid cell rests in the lingual muscles. Whole-body scanning, carried out in connection with administration of radioiodine for ablation of remaining thyroid tissue, disclosed an unexpected area of increased uptake in the epigastrium. Sonography and CT scans failed to demonstrate any corresponding morphological abnormality. Following a further dose of radioiodine 4 months later, no areas of increased uptake were noted.
一名17岁女性接受了手术切除一个无痛性颏下肿块,该肿块被推测为甲状舌管囊肿。组织学检查显示为乳头状甲状腺癌,侵犯周围结缔组织。为计划中的全甲状腺切除术做准备而进行的锝-99m扫描未显示甲状腺组织。随后的碘-123扫描显示,在喉上方约3厘米处有一个摄取增加的区域,但没有正常甲状腺组织。在进一步对舌根进行手术探查时获取的组织学切片显示,舌肌中有散在的甲状腺细胞残余。在给予放射性碘以消融残留甲状腺组织的过程中进行的全身扫描显示,上腹部有一个意外的摄取增加区域。超声检查和CT扫描均未显示任何相应的形态学异常。4个月后再次给予放射性碘后,未发现摄取增加的区域。