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氢氧化钙、Sealapex和Endofill根管充填后延迟牙再植愈合过程的分析:大鼠的微观研究

Analysis of the healing process in delayed tooth replantation after root canal filling with calcium hydroxide, Sealapex and Endofill: a microscopic study in rats.

作者信息

Negri Márcia Regina, Panzarini Sônia Regina, Poi Wilson Roberto, Sonoda Celso Koogi, Gulinelli Jéssica Lemos, Saito Célia Tomiko Matida Hamata

机构信息

Department of Surgery and Integrated Clinics, School of Dentistry of Araçatuba, São Paulo State University (UNESP), Araçatuba, SP, Brazil.

出版信息

Dent Traumatol. 2008 Dec;24(6):645-50. doi: 10.1111/j.1600-9657.2008.00682.x.

Abstract

The major concern in the therapeutics of tooth replantation refers to the occurrence of root resorption and different approaches have been proposed to prevent or treat these complications. The purpose of this study was to evaluate tissue response to delayed replantation of anterior rat teeth treated endodontically using calcium hydroxide, Sealapex, and Endofill without the placement of gutta-percha cones. Thirty rats had their right upper incisor extracted and maintained in dry storage for 60 min. After removal of the dental papilla, enamel organ, pulp tissue, and periodontal ligament remnants, the teeth were immersed in 2% sodium fluoride phosphate acidulated, pH 5.5, for 10 min. The root canals were dried with absorbent paper points and the teeth were assigned to three groups (n = 10) according to the filling material. Group I - calcium hydroxide and propyleneglycol paste, Group II - Sealapex, and Group III - Endofill. The sockets were irrigated with saline and the teeth were replanted. Replacement resorption, inflammatory resorption and ankylosis were observed in all groups. Although the occurrence of inflammatory resorption was less frequent in Group I, there were no statistically significant differences among the groups. It may be concluded that compared to the paste, filling the root canals with Sealapex and Endofill sealers without the placement of gutta-percha cones did not provide better results.

摘要

牙齿再植治疗中的主要问题是牙根吸收的发生,并且已经提出了不同的方法来预防或治疗这些并发症。本研究的目的是评估使用氢氧化钙、Sealapex和Endofill进行根管治疗且不放置牙胶尖的情况下,大鼠前牙延迟再植后的组织反应。30只大鼠的右上切牙被拔除并在干燥环境中保存60分钟。去除牙髓乳头、成釉器、牙髓组织和牙周膜残余物后,将牙齿浸入pH值为5.5的2%磷酸酸化氟化钠溶液中10分钟。用吸水纸尖干燥根管,然后根据填充材料将牙齿分为三组(n = 10)。第一组 - 氢氧化钙和丙二醇糊剂,第二组 - Sealapex,第三组 - Endofill。用生理盐水冲洗牙槽窝并将牙齿再植。所有组均观察到替代性吸收、炎性吸收和牙骨质粘连。虽然第一组中炎性吸收的发生率较低,但各组之间无统计学显著差异。可以得出结论,与糊剂相比,使用Sealapex和Endofill封闭剂填充根管且不放置牙胶尖并不能取得更好的效果。

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