Ferreira Manuel Marques, Botelho Maria Filomena, Abrantes Margarida, Carvalho Lina, Carrilho Eunice
Department of Dentistry, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Eur J Dent. 2017 Jan-Mar;11(1):89-93. doi: 10.4103/ejd.ejd_106_16.
This study aims to analyze the effect of new root canal based silicate cement, in rat teeth after late replantation, comparing with calcium hydroxide (CH) in preventing tooth root resorption.
The study group included 16 Wistar rats in which the upper right central incisors were extracted and were left on a worktable for 60 min, simulating a case of tooth avulsion, after had been anesthetized. One group, (Group I), the canals were filled with CH past, before replantation. The second groups of teeth, (Group II), the canals were filled with mineral trioxide aggregate-Fillapex (MTAF). After removal, the blood clot of the socket, with saline solution irrigation, the teeth were replanted into their original socket, and splinted with silk 3/0. The rats were sacrificed 8 weeks after replantation and the specimens were prepared for histologic and histomorphometric analyses. The areas of inflammatory and replacement resorptions were selected and quantified. These data for each group of teeth were evaluated and analyzed using the Mann-Whitney test ( = 0.05).
All the replanted teeth in both groups survived. Although root canal filled with MTAF provide better results than with CH past concerning inflammatory and replacement resorption, there was no statistical difference ( = 0.527).
本研究旨在分析新型根管硅酸盐水泥在大鼠牙齿晚期再植后的效果，与氢氧化钙（CH）相比，观察其在预防牙根吸收方面的作用。
研究组包括16只Wistar大鼠，将其上颌右侧中切牙拔除，在麻醉后置于工作台上60分钟，模拟牙齿脱位情况。一组（I组），在再植前用CH糊剂充填根管。第二组牙齿（II组），根管内充填三氧化矿物凝聚体-菲拉派克（MTAF）。去除牙槽窝内的血凝块，用生理盐水冲洗后，将牙齿再植回原牙槽窝，并用3/0丝线固定。再植8周后处死大鼠，制备标本进行组织学和组织形态计量学分析。选择并量化炎症性吸收和替代性吸收的面积。每组牙齿的数据采用Mann-Whitney检验进行评估和分析（α = 0.05）。
两组所有再植牙齿均存活。尽管在炎症性吸收和替代性吸收方面，用MTAF充填根管比用CH糊剂效果更好，但差异无统计学意义（P = 0.527）。
