Satter Elizabeth K, Gendernalik Sarah B, Galeckas Kenneth J
Department of Dermatology, Naval Medical Center San Diego, 34520 Bob Wilson Dr, Suite 300, San Diego, CA 92134-2300, USA.
J Am Acad Dermatol. 2009 May;60(5):841-8. doi: 10.1016/j.jaad.2008.10.001. Epub 2008 Nov 20.
The advent of electron microscopy and immunohistochemical stains allowed for reclassification of the histiocytoses based on the predominant cell in the infiltrate. Although the current schema simplicity provides a good foundation, some patients display overlapping clinical and immunohistochemical features that defy classification. The patient herein illustrates bridging between histiocytic disorders. Through this case we review the various conditions classified under the non-Langerhans cell histiocytosis and Langerhans cell histiocytosis rubric.
电子显微镜和免疫组织化学染色的出现，使得基于浸润中占主导地位的细胞对组织细胞增多症进行重新分类成为可能。尽管当前的分类方案简单明了，提供了良好的基础，但一些患者表现出重叠的临床和免疫组织化学特征，难以进行分类。本文所述患者展示了组织细胞疾病之间的过渡情况。通过这个病例，我们回顾了归类于非朗格汉斯细胞组织细胞增多症和朗格汉斯细胞组织细胞增多症范畴下的各种病症。
