Ramos R, Mascarenhas J, Duarte P, Vicente C, Casteleiro C
Servicio de Aparato Digestivo, Hospital Universitário de Covilhã, Quinta do Alvito, 6000-251 Covilhã, Portugal.
Rev Esp Enferm Dig. 2008 Sep;100(9):583-5. doi: 10.4321/s1130-01082008000900010.
Acute esophageal necrosis has been considered a rare event. It is defined as the presence of diffuse dark pigmentation of the esophagus on upper endoscopy. Its incidence has not yet been established. The pathogenesis remains unknown.
A retrospective analysis of clinical, laboratory, endoscopic, and histological data, and of the clinical course of 11 patients with acute necrotizing esophagitis was carried out over a 2-year period.
Among 3,976 patients who underwent upper endoscopy, 11 (0.28%) with acute esophageal necrosis were identified. Nutritional status was poor for 6 patients. Complete resolution of acute esophageal necrosis without further recurrence was observed in 4. One stricture appeared during follow-up and other patient developed new-onset acute esophageal necrosis. Seven patients died, but no death was directly related to acute esophageal necrosis.
The incidence of acute esophageal necrosis in our series is 0.28%. Acute esophageal necrosis is associated with high mortality rates.
急性食管坏死一直被认为是一种罕见事件。它被定义为上消化道内镜检查时食管出现弥漫性深色色素沉着。其发病率尚未确定。发病机制仍不清楚。
对11例急性坏死性食管炎患者在2年期间的临床、实验室、内镜和组织学数据以及临床病程进行回顾性分析。
在3976例行上消化道内镜检查的患者中，发现11例（0.28%）有急性食管坏死。6例患者营养状况较差。4例急性食管坏死完全缓解且无进一步复发。随访期间出现1例狭窄，另1例患者发生新发急性食管坏死。7例患者死亡，但无死亡与急性食管坏死直接相关。
我们系列研究中急性食管坏死的发病率为0.28%。急性食管坏死与高死亡率相关。
