Pence Brian Wells, Thielman Nathan M, Whetten Kathryn, Ostermann Jan, Kumar Virender, Mugavero Michael J
Health Inequalities Program, Center for Health Policy, Duke University, Durham, NC 27708, USA.
AIDS Patient Care STDS. 2008 Nov;22(11):869-77. doi: 10.1089/apc.2008.0022.
Alcohol and drug use are common among HIV-infected patients and are important determinants of secondary transmission risk and medication adherence. As part of the Coping with HIV/AIDS in the Southeast (CHASE) Study, 611 HIV-infected patients were consecutively recruited from eight clinical care sites in five southeastern U.S. states in 2001-2002. We examined the distribution and predictors of alcohol and drug use in this sample with an emphasis on psychosocial predictors of use. In the prior 9 months, 27% of participants drank alcohol and 7% drank to intoxication at least weekly. The most common drugs used at least weekly were marijuana (12%) and crack (5%); 11% used a non-marijuana drug. 7% reported polysubstance use (use of multiple substances at one time) at least weekly. Injection drug use was rare (2% injected at least once in the past 9 months). There were few differences in alcohol and drug use across sociodemographic characteristics. Stronger adaptive coping strategies were the most consistent predictor of less frequent alcohol and drug use, in particular coping through action and coping through relying on religion. Stronger maladaptive coping strategies predicted greater frequency of drinking to intoxication but not other measures of alcohol and drug use. Those with more lifetime traumatic experiences also reported higher substance use. Interventions that teach adaptive coping strategies may be effective in reducing alcohol and substance use among HIV-positive persons.
艾滋病毒感染患者中酒精和药物使用很常见,并且是二次传播风险和药物依从性的重要决定因素。作为东南部应对艾滋病毒/艾滋病(CHASE)研究的一部分,2001年至2002年期间,从美国东南部五个州的八个临床护理点连续招募了611名艾滋病毒感染患者。我们研究了该样本中酒精和药物使用的分布及预测因素,重点关注使用的心理社会预测因素。在之前的9个月里,27%的参与者饮酒,7%的参与者至少每周一次饮酒至醉酒状态。至少每周使用的最常见药物是大麻(12%)和快克可卡因(5%);11%的人使用非大麻类药物。7%的人报告至少每周一次使用多种物质(同时使用多种物质)。注射吸毒很少见(2%的人在过去9个月里至少注射过一次)。不同社会人口学特征的人群在酒精和药物使用方面几乎没有差异。更强的适应性应对策略是饮酒和药物使用频率较低最一致的预测因素,特别是通过行动应对和依靠宗教应对。更强的适应不良应对策略预示着醉酒饮酒频率更高,但对酒精和药物使用的其他衡量指标没有影响。有更多终身创伤经历的人也报告有更高的物质使用情况。教授适应性应对策略的干预措施可能对减少艾滋病毒阳性者的酒精和物质使用有效。