Keenan Niall G, Grasso Agata, Locca Didier, Varghese Anitha, Roughton Michael, Gatehouse Peter D, Firmin David N, Pennell Dudley J
Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
J Magn Reson Imaging. 2008 Dec;28(6):1476-82. doi: 10.1002/jmri.21582.
To compare a multislab three-dimensional volume-selective fast spin-echo (FSE) magnetic resonance (MR) sequence with a routine two-dimensional FSE sequence for quantification of carotid wall volume.
One hundred normal subjects (50 men, mean age 44.6 years) underwent carotid vessel wall MR using 2D and 3D techniques. Carotid artery total vessel volume, lumen volume, wall volume, and wall/outer wall (W/OW) ratio were measured over 20 contiguous slices. Two- (2D) and three-dimensional (3D) results were compared.
The mean difference between 2D and 3D datasets (as a percentage of the mean absolute value) was 1.7% for vessel volume, 4.9% for lumen volume, 4.7% for wall volume, and 5.8% for W/OW ratio. There was good correlation between 2D and 3D models for total vessel volume (R(2) = 0.93, P < 0.001), lumen area (R(2) = 0.92, P < 0.001), and wall volume (R(2) = 0.77, P < 0.001). The correlation for the W/OW ratio was weaker (R(2) = 0.30; P < 0.001). The signal-to-noise ratio (SNR) for the 3D technique was 2.1-fold greater than for the 2D technique (P < 0.001). When using the 3D sequence, scan time was reduced by 63%.
Multislab volume selective 3D FSE carotid arterial wall imaging performs similarly to a conventional 2D technique, but with over twice the SNR and substantially reduced scan time.
比较多层面三维容积选择快速自旋回波（FSE）磁共振（MR）序列与常规二维FSE序列对颈动脉壁容积的定量分析。
100名正常受试者（50名男性，平均年龄44.6岁）采用二维和三维技术进行颈动脉血管壁MR检查。在20个连续层面上测量颈动脉总血管容积、管腔容积、壁容积以及壁/外壁（W/OW）比值。比较二维（2D）和三维（3D）结果。
2D和3D数据集之间的平均差异（以平均绝对值的百分比表示）为：血管容积1.7%，管腔容积4.9%，壁容积4.7%，W/OW比值5.8%。2D和3D模型在总血管容积（R(2)=0.93，P<0.001）、管腔面积（R(2)=0.92，P<0.001）和壁容积（R(2)=0.77，P<0.001）方面具有良好的相关性。W/OW比值的相关性较弱（R(2)=0.30；P<0.001）。3D技术的信噪比（SNR）比2D技术高2.1倍（P<0.001）。使用3D序列时，扫描时间减少了63%。
多层面容积选择3D FSE颈动脉壁成像与传统2D技术表现相似，但信噪比提高了两倍多，扫描时间大幅缩短。
