Yang Xuhong, Chen Lei, Liu Yonghong, Zeng Dong, Tang Yufeng, Yan Bo, Lin Xu, Liu Ling, Xu Hongru, Zhou Dong
Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Epilepsy Res. 2009 Feb;83(2-3):97-102. doi: 10.1016/j.eplepsyres.2008.09.010. Epub 2008 Nov 22.
To quantitatively analyze trajectory of movement in automatisms with temporal lobe epilepsy (TLE) and frontal lobe epilepsy (FLE).
Twenty markers were attached to chosen body parts of patients, and 10 videos of seizures were recorded. The obtained videos were converted into digital matrices. Motor trajectories were established, the amplitude, frequency, limb distal-proximal amplitude ratio, and shoulder-abdominal amplitude ratio were calculated, analyzed and compared between two types of epilepsy.
The average of transient limb distal-proximal ratios in automatism patients with TLE was >3, which suggested that distal limb movements during TLE were predominant. However, the transient limb distal-proximal ratio in patients with FLE was <3, which indicated the predominance of proximal movements. The differences of motor trajectories between these two types of epilepsy were statistically significant.
The quantification system may pave a new way for semiology study of epilepsy and is important in differential diagnosis of different types of epilepsy.
定量分析颞叶癫痫（TLE）和额叶癫痫（FLE）自动症的运动轨迹。
在患者选定的身体部位附着20个标记物，记录10次癫痫发作的视频。将获得的视频转换为数字矩阵。建立运动轨迹，计算、分析并比较两种癫痫类型的振幅、频率、肢体远 - 近端振幅比和肩 - 腹振幅比。
TLE自动症患者的瞬时肢体远 - 近端平均比值>3，这表明TLE期间肢体远端运动占主导。然而，FLE患者的瞬时肢体远 - 近端比值<3，这表明近端运动占主导。这两种癫痫类型的运动轨迹差异具有统计学意义。
该量化系统可能为癫痫的症状学研究开辟一条新途径，对不同类型癫痫的鉴别诊断具有重要意义。
