Lipman T O
GI-Hepatology-Nutrition Section, Veterans Affairs Medical Center, Washington, DC.
Hematol Oncol Clin North Am. 1991 Feb;5(1):91-102.
Cancer-related malnutrition is associated with poor prognosis. Although logic would dictate that nutritional support should improve malnutrition and thus outcome, when tested by controlled clinical trials, this has not borne out. With the exception of bone marrow transplantation, routine specialized nutritional support, particularly parenteral nutrition, has not demonstrated consistent therapeutic benefit with respect to any outcome measure and may be associated with harm to patients. The clinician must carefully select appropriate indications for specialized nutritional support in cancer patients.
癌症相关营养不良与预后不良相关。虽然从逻辑上讲营养支持应能改善营养不良并进而改善预后，但经对照临床试验检验，情况并非如此。除骨髓移植外，常规的特殊营养支持，尤其是肠外营养，在任何预后指标方面均未显示出一致的治疗益处，而且可能对患者有害。临床医生必须谨慎选择癌症患者特殊营养支持的合适指征。
