Paediatr Child Health. 2007 May;12(5):401-18. doi: 10.1093/pch/12.5.401.
Hyperbilirubinemia is very common and usually benign in the term newborn infant and the late preterm infant at 35 and 36 completed weeks' gestation. Critical hyperbilirubinemia is uncommon but has the potential for causing long-term neurological impairment. Early discharge of the healthy newborn infant, particularly those in whom breastfeeding may not be fully established, may be associated with delayed diagnosis of significant hyperbilirubinemia. Guidelines for the prediction, prevention, identification, monitoring and treatment of severe hyperbilirubinemia are presented.
高胆红素血症在足月儿以及妊娠35和36周的晚期早产儿中非常常见,且通常为良性。重度高胆红素血症并不常见,但有可能导致长期神经功能损害。健康新生儿过早出院,尤其是那些母乳喂养可能尚未完全建立的新生儿,可能与严重高胆红素血症的诊断延迟有关。本文提出了重度高胆红素血症的预测、预防、识别、监测及治疗指南。