重温二十恐惧症。
Vigintiphobia revisited.
作者信息
Watchko Jon F
机构信息
Division of Neonatology and Developmental Biology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
出版信息
Pediatrics. 2005 Jun;115(6):1747-53. doi: 10.1542/peds.2004-1748.
In this review the historical tenets and evidence-based clinical research in support of a bilirubin exchange threshold of >20 mg/dL for the healthy term neonate are revisited. In addition, a hypothesis is ventured that recent cases of kernicterus are related in part to changes in population factors coupled with genetic predispositions that have unmasked an unappreciated potential for marked neonatal hyperbilirubinemia.
在本综述中，我们重新审视了支持健康足月儿胆红素换血阈值>20mg/dL的历史原则和循证临床研究。此外，我们提出一个假说，即近期的核黄疸病例部分与人群因素的变化以及遗传易感性有关，这些因素揭示了未被认识到的新生儿显著高胆红素血症的潜在可能性。
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