Mérelle Saskia Y M, Sorbi Marjolijn J, van Doornen Lorenz J P, Passchier Jan
Department of Medical Psychology and Psychotherapy, Erasmus University Medical Center, Rotterdam, the Netherlands.
Headache. 2008 Oct;48(9):1311-25. doi: 10.1111/j.1526-4610.2007.01043.x.
To evaluate the changes at 6-month follow-up after a home-based behavioral training (BT) provided by lay trainers with migraine to small groups of fellow patients.
The need for self-management programs and cost-effective treatments gave rise to this study.
In a previous randomized controlled trial, we compared the BT group with a waitlist-control group, receiving usual care. The control group was trained directly after their waitlist period. The present study examined the follow-up results in both groups and measurements were held pre BT, post BT, and at 6-month follow-up.
Six months after BT, 42% was categorized as responders (>or=-50% decrease in attack frequency), 42% did not change (-49 to 49%), and 16% responded adversely (>or=50% increase). In the group as a whole (n = 95), attack frequency significantly decreased from 3.0 attacks at baseline to 2.5 post BT and to 2.3 at 6-month follow-up (-23%, medium effect size 0.6). The strong improvements of perceived control over and self-confidence in attack prevention were maintained at follow-up. Disability and health status were unchanged but quality of life significantly improved over time (P = .007). BT was more beneficial for patients who entered the training with a high attack frequency. Linear regression analysis demonstrated that a stronger belief at baseline that the occurrence of migraine is due to chance (external control) significantly predicted a lower attack frequency at follow-up.
Lay trainers with migraine can train small groups of fellow patients at home in behavioral attack prevention. At 6-month follow-up, attack frequency and quality of life were significantly but modestly improved and feelings of control and self-confidence remained strongly improved.
评估由偏头痛患者外的非专业培训人员为一小群偏头痛患者提供家庭行为训练(BT)6个月后的随访变化情况。
自我管理项目的需求和具有成本效益的治疗方法促成了本研究。
在之前的一项随机对照试验中,我们将行为训练组与接受常规护理的候补对照组进行了比较。对照组在候补期结束后直接接受训练。本研究检查了两组的随访结果,并在行为训练前、行为训练后以及6个月随访时进行了测量。
行为训练6个月后,42%的患者被归类为有反应者(发作频率降低≥50%),42%的患者无变化(降低或增加49%以内),16%的患者反应不佳(发作频率增加≥50%)。在整个组(n = 95)中,发作频率从基线时的3.0次显著降低至行为训练后的2.5次以及6个月随访时的2.3次(降低23%,中等效应量为0.6)。在随访中,对预防发作的感知控制和自信心的显著改善得以维持。残疾和健康状况未改变,但生活质量随时间显著改善(P = 0.007)。行为训练对发作频率高的患者更有益。线性回归分析表明,基线时更强的认为偏头痛发作是由于偶然因素(外部控制)的信念显著预测了随访时较低的发作频率。
患有偏头痛的非专业培训人员可以在家中对一小群偏头痛患者进行预防发作的行为训练。在6个月的随访中,发作频率和生活质量有显著但适度的改善,控制感和自信心仍有显著改善。