一种用于乳腺癌前哨淋巴结手术的新型术中γ相机。
A new intraoperative gamma camera for the sentinel lymph node procedure in breast cancer.
作者信息
Mathelin Carole, Salvador Samuel, Bekaert Virgile, Croce Sabrina, Andriamisandratsoa Norosoa, Liégeois Philippe, Prados Eric, Guyonnet Jean-Louis, Grucker Daniel, Brasse David
机构信息
CHRU, Service de Gynécologie-Obstétrique, Hôpital Civil, F-67091 Strasbourg, France.
出版信息
Anticancer Res. 2008 Sep-Oct;28(5B):2859-64.
AIM
This study aimed at evaluating the performance of an intraoperative gamma camera, named CarolIReS, to detect axillary drainage and to assess the removal of sentinel lymph nodes (SLN) in breast surgery.
PATIENTS AND METHODS
SLN biopsy was performed on 25 patients and the CarolIReS camera was used preoperatively to localize SLNs. During surgery, individual removal of SLNs was performed using a gamma probe and their activity was measured with a gamma ray counter. At the end of surgery, the CarolIReS camera was used again to check the quality of surgery which was followed by surgical excision for remaining SLNs.
RESULTS
The detection efficiency of the CarolIReS camera was 2.2 cps/kBq for 99"Tc activity in SLNs. In one case, it allowed the detection of a residual SLN with a low activity (0.5 kBq) which was massively metastatic.
CONCLUSION
Intraoperative cameras could be used to improve the efficiency of the SLN procedure.
目的
本研究旨在评估一款名为CarolIReS的术中γ相机在乳腺手术中检测腋窝引流以及评估前哨淋巴结（SLN）切除情况的性能。
患者与方法
对25例患者进行了前哨淋巴结活检，并在术前使用CarolIReS相机定位前哨淋巴结。手术过程中，使用γ探针逐个切除前哨淋巴结，并用γ射线计数器测量其活性。手术结束时，再次使用CarolIReS相机检查手术质量，随后对剩余的前哨淋巴结进行手术切除。
结果
对于前哨淋巴结中的99锝活性，CarolIReS相机的检测效率为2.2计数每秒/千贝克勒尔。在1例病例中，它检测到了一个活性较低（0.5千贝克勒尔）但有大量转移的残留前哨淋巴结。
结论
术中相机可用于提高前哨淋巴结手术的效率。
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